Feasibility of End-tidal Oxygen Concentration Monitoring During Preoxygenation for Intubation in the Intensive Care Unit.

Launched by CENTRE HOSPITALIER RÉGIONAL D'ORLÉANS · Jun 3, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how reliable a specific method of measuring oxygen levels is during a procedure called intubation, which is often needed for critically ill patients in the intensive care unit (ICU). Normally, doctors check oxygen levels in the operating room using a method called end-tidal oxygen concentration (EtO2), but in the ICU, the conditions are different and it may not be as accurate. This study aims to compare the EtO2 measured from a face mask to that measured in the throat to see if the face mask readings can be trusted in these emergency situations.

To participate in this trial, you must be at least 18 years old and need intubation due to serious breathing problems, which might include rapid breathing or low oxygen levels. Participants will receive preoxygenation, a process to increase oxygen in the blood before intubation, using noninvasive ventilation. This study is currently recruiting participants, and it’s important to know that certain conditions, such as being pregnant or having specific allergies, may exclude someone from joining. If you or a family member are considering participation, you can expect to be monitored closely during the process to ensure safety and effectiveness.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Requiring an intubation in ICU for acute respiratory failure defined as a respiratory rate ≥ 25/min or clinical signs of respiratory distress or hypoxemia defined as oxygen requirement ≥ 15L/min or FiO2 ≥80% to maintain SpO2 ≥92% or a PaO2/FiO2 ratio \<100 mmHg
• • With preoxygenation by noninvasive ventilation
• Exclusion Criteria:
• • Intubation for cardiac arrest
• • EtO2 monitoring not available
• • Pulsed oxygen saturation monitoring specific for the study not available
• • Preoxygenation by high-flow nasal oxygen therapy or bag-mask ventilation
• • Allergy to lidocaine (for local nasal anesthesia)
• • Previously
• • Patient not affiliated or excluded from social protection, or under law protection (namely minors, pregnant or breastfeeding women, persons deprived of their liberty by court or administrative decision)
• • Previously included in the study