Ventilator Aspiration With PneuX (PneuX vs Standard Care Feasibility RCT)

Launched by CARDIFF AND VALE UNIVERSITY HEALTH BOARD · Jun 6, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating the use of a special type of breathing tube called the PneuX Endotracheal Tube (ETT) in patients who need help breathing on a ventilator. The goal is to see if this new tube can help prevent lung infections, known as ventilator-associated pneumonia, compared to the standard breathing tube. The study will take place at the University Hospital of Wales and will involve 50 patients who are critically ill and need to be intubated, which means having a tube placed in their windpipe to assist with breathing.

To be eligible for the study, patients must be at least 18 years old and require intubation, expecting to be on the ventilator for at least 24 hours after being randomly assigned to either the PneuX tube or the standard tube. Participants can expect to be monitored closely for how well the new tube works, any side effects, and details about their recovery, such as the length of their stay in the intensive care unit (ICU) and the hospital. This study will help researchers gather important information that could lead to larger studies in the future to see if the PneuX tube is a better option for patients needing ventilatory support.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years old (no upper age)
• • Patient required endotracheal intubation
• • Expect to remain intubated for 24 hours post randomisation
• Exclusion Criteria:
• • The person intubating the patient assesses that the patient has already aspirated.
• • GCS 7 or less on presentation to hospital
• • Patient is pregnant
• • Patient has tracheostomy
• • Patient has gastrectomy
• • Patients who have been intubated prior to arrival at hospital
• • Patients who are already endotracheally intubated and require a tube change.