Evaluation of Chlorhexidine Plus Hyaluronic Acid Mouthwash in Surgical Wound Healing Following Third Molar Surgery (CLOR_4)

Launched by UNIVERSITY OF PISA · Jun 7, 2022

Keywords

ClinConnect Summary

This clinical trial, called CLOR_4, is studying how well a special mouthwash containing chlorhexidine and hyaluronic acid helps healing after third molar surgery, which is commonly known as wisdom tooth removal. The researchers want to see if this mouthwash can improve the recovery of the gum tissues following the surgery.

To participate, you need to be a healthy adult between 18 and 70 years old who is scheduled for third molar surgery and willing to follow the study's guidelines. However, if you are pregnant, breastfeeding, or have certain health conditions, you may not be eligible. If you join the study, you can expect to use the mouthwash as directed and attend follow-up visits to monitor your healing process. This trial is currently recruiting participants, and it aims to find out if the mouthwash can make a difference in recovery after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • males or females of age range between 18 and 70 years,
• • good health status,
• • indication to perform third molar surgery,
• • patients willing to give informed consent,
• • compliance to the study follow-up,
• Exclusion Criteria:
• • pregnancy or breast-feeding,
• • indication to antibiotic therapy prior to surgical treatment,
• • chronic infections,
• • systemic diseases (including cardiovascular, pulmonary, cerebral, and metabolic diseases),
• • previous therapy with the mouth rinses employed in the present study, and
• • smoking habit (\>20 cigarettes per day, and/or pipe or cigar smoking).