The Relationship Between Long-term Oral Anti Hepatitis B Nucleoside Analogs and Hepatic Steatosis
Launched by THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY · Jun 9, 2022
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This is a single-center, prospective, observational study involving chronic hepatitis B patients from the Second Affiliated Hospital of Chongqing Medical University.
Research implementation process and route
Recruitment object: Patients with chronic hepatitis B, defined as persistent hepatitis B surface antigen positive for ≥ 6 months, (aged ≥ 18, treatment-naive ) were consecutively recruited for outpatient routine examination between July 2021 and December 2022. We excluded patients with prior history of hepatocellular carcinoma, concomitant hepatitis C virus or human immunodeficiency v...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Willing and able to sign informed consent.
- • Male or female.
- • 18 ≤ age≤ 80.
- • Clinical diagnosis of chronic hepatitis B.
- • Has not received anti HBV treatment.
- Exclusion Criteria:
- • With prior history of HCC
- • Concomitant HCV or HIV
- • Primary biliary cholangitis
- • Wilson's disease
- • Autoimmune hepatitis
- • Significant alcohol intake (≥ 30 g per day for male, or ≥ 20 g per day for female)
- • Taking steatogenic medications
- • Prior liver transplantation
About The Second Affiliated Hospital Of Chongqing Medical University
The Second Affiliated Hospital of Chongqing Medical University is a leading healthcare institution dedicated to advancing medical research and patient care through innovative clinical trials. As a prominent academic hospital in China, it combines cutting-edge medical technology with a strong emphasis on education and training for healthcare professionals. The hospital is committed to conducting high-quality, ethically sound clinical research that contributes to the development of new therapies and enhances healthcare outcomes. With a multidisciplinary team of experts, the Second Affiliated Hospital fosters collaboration and strives to address critical health challenges through rigorous scientific investigation.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chongqing, Chongqing, China
Patients applied
Trial Officials
Dazhi Zhang, Doctor
Principal Investigator
The Second Affiliated Hospital of Chongqing Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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