Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025

Launched by BERNARDINO CLAVO, MD, PHD · Jun 9, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the effects of ozone therapy on patients dealing with severe pain and other difficult health issues, such as radiation damage, chemotherapy side effects, and delayed wound healing. The goal is to see if adding ozone therapy can improve the quality of life for patients who haven’t found relief from traditional treatments and have been referred to the Chronic Pain Unit at the Hospital Universitario de Gran Canaria Dr. Negrín from June 2022 to December 2025.

To participate, patients must be at least 18 years old and have been identified as needing additional help for their symptoms through ozone therapy. They should not have any major health issues that prevent them from participating or any known allergies to ozone. Participants can expect to undergo ozone therapy as part of their treatment plan, and they will be closely monitored throughout the study to assess how this therapy affects their pain and overall well-being. If you or a loved one are considering joining this study, it’s important to discuss any questions or concerns with your healthcare provider.

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Eligibility criteria

• Inclusion Criteria:
• • 1. Adults \> = 18 years old.
• • 2. Patients submitted to the Chronic Pain Unit of the Hospital Universitario de Gran Canaria Dr. Negrín for symptomatic/palliative treatment with ozone therapy because conventional treatment does not exist, it has been unsuccessful, or it is associated with high risk or high morbidity.
• • 3. After evaluation of symptoms and patients, it exists a potential benefit of adding ozone treatment to the current treatment.
• • 4. Patients have no contraindications for ozone treatment.
• • 5. Patients have signed and dated the informed consent for the compassionated ozone treatment and the specific informed consent for this study
• Exclusion Criteria:
• • 1. Age \< 18 years old.
• • 2. Psychiatric illness or social situations that would limit compliance with study requirements.
• • 3. Those who are incapable to fill in the scales used to measure variables.
• • 4. Hemodynamically or clinically unstable patients or uncontrolled severe illness.
• • 5. Uncontrolled cancer disease requiring chemotherapy treatment.
• • 6. Life expectancy \< 6 months
• • 7. Contraindication or disability or to attend scheduled treatments.
• • 8. Known allergy to ozone.
• • 9. Pregnancy at the time of enrollment (for systemic ozone therapy). 10 Hemochromatosis (for systemic ozone therapy).
• • 11. Known significant glucose-6-phosphate dehydrogenase deficiency (favism, acute hemolytic anemia) (for systemic ozone therapy).
• • 12. Patients who do not meet all the inclusion criteria