Preoperative Embolization of the Inferior Mesenteric Artery in Colorectal Surgery
Launched by UNIVERSITY HOSPITAL, GRENOBLE · Jun 15, 2022
Trial Information
Current as of July 06, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, called EPAMIR, is investigating a procedure known as preoperative embolization of the inferior mesenteric artery for patients undergoing colorectal surgery. This means that before surgery, doctors will temporarily block the blood flow to a specific artery to improve surgical outcomes. The trial is currently recruiting participants aged 65 to 74 who are scheduled for surgery on the left side of the colon or rectum.
To be eligible, participants need to be adults who can benefit from this type of surgery, and they must have given their written consent to join the study. However, individuals with a history of certain abdominal surgeries, severe kidney issues, or specific allergies, as well as pregnant or nursing women, cannot participate. If you join this trial, you will receive care and monitoring related to the embolization technique, helping researchers understand how it can improve surgery results. This study aims to gather valuable information that could enhance treatment for future patients in similar situations.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients
- • Patient to benefit from left colonic surgery or rectal surgery with upper ligation of the inferior mesenteric artery and colorectal or colo anastomosis
- • Person affiliated to or benefiting from social security
- • Person who has given written informed consent
- Exclusion Criteria:
- • History of digestive resection or abdominal aorta surgery
- • Renal failure with GFR \< 30 ml/min (MDRD)
- • History of severe allergy to iodine contrast medium
- • Pregnant, parturient, lactating women
- • Patient subject to a legal protection measure or unable to express his non-opposition (guardianship, curatorship)
- • Patient deprived of liberty by judicial or administrative decision
About University Hospital, Grenoble
The University Hospital of Grenoble is a leading academic medical center dedicated to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent sponsor of clinical trials, the hospital leverages its expertise in various medical disciplines to facilitate cutting-edge studies that aim to improve treatment outcomes and enhance patient safety. With a strong commitment to collaboration, the University Hospital of Grenoble engages in partnerships with academic institutions, industry leaders, and regulatory bodies to drive scientific discovery and translate research findings into clinical practice. Its state-of-the-art facilities and multidisciplinary teams ensure rigorous adherence to ethical standards and regulatory guidelines, fostering an environment where groundbreaking research can thrive.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Clermont Ferrand, , France
Grenoble, , France
Grenoble, , France
Patients applied
Trial Officials
Julien GHELFI, MD
Principal Investigator
Grenoble Alpes University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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