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Search / Trial NCT05424302

Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy

Launched by UNIVERSITY OF BRITISH COLUMBIA · Jun 14, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Virtual Reality Video Games Peripheral Vestibular Disorders Benign Paroxysmal Positional Vertigo Meniere Disease Vestibular Neuritis Vestibular Neuronitis Labyrinthitis Herpes Zoster Oticus

ClinConnect Summary

This clinical trial is studying how the location of a problem in the inner ear, known as a vestibular disorder, affects the success of a special virtual reality therapy designed to help patients with balance issues. The researchers want to find out if patients with different types of vestibular disorders, such as Meniere disease or benign paroxysmal positional vertigo, respond differently to this at-home therapy. They will recruit 50 patients who have been diagnosed with these conditions and will randomly assign them to either a group that uses the virtual reality therapy or a control group. After 4 to 8 weeks of treatment, participants will answer questions about their symptoms to see how well the therapy worked.

To take part in this trial, participants need to be at least 18 years old and have been dealing with their vestibular disorder for three months or more. They should have a specific diagnosis confirmed through certain tests. However, pregnant individuals and those with central vestibular disorders (which involve problems in the brain rather than the inner ear) cannot participate. This study will help improve understanding of how different vestibular conditions respond to virtual reality therapy, potentially leading to better treatment options for patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants diagnosed with chronic (≥3 months) unilateral or bilateral peripheral vestibular disorders such as vestibular neuritis, labyrinthitis, Ramsay Hunt syndrome, ischemic lesion and trauma.
  • Diagnosis made using caloric testing (≥25% reduced vestibular response) and either ocular vestibular evoked myogenic potential (oVEMP) or cervical vestibular evoked myogenic potential (cVEMP) testing.
  • Participants prescribed vestibular rehabilitation
  • Participants ≥18 years of age
  • Access to an android or iOS smart phone
  • Exclusion Criteria:
  • Pregnant participants
  • Participant diagnosed with a central vestibular disorder

About University Of British Columbia

The University of British Columbia (UBC) is a leading research institution located in Vancouver, Canada, renowned for its commitment to advancing health sciences through innovative research and education. As a prominent clinical trial sponsor, UBC leverages its interdisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes across various medical fields. The university fosters collaborations with healthcare professionals, industry partners, and community stakeholders to translate research findings into practical applications, thereby contributing to the global advancement of medicine and public health.

Locations

Vancouver, British Columbia, Canada

Patients applied

0 patients applied

Trial Officials

Desmond A Nunez, MD, MBA

Principal Investigator

Division of Otolaryngology, Department of Surgery, The University of British Columbia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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