Children's Bipolar Network Treatment Trial I

Launched by UNIVERSITY OF CALIFORNIA, LOS ANGELES · Jun 15, 2022

Keywords

ClinConnect Summary

The Children's Bipolar Network Treatment Trial I is a study designed to better understand and treat children and teenagers aged 9 to 19 who have bipolar disorder and related conditions. The trial aims to accurately identify these young patients and explore factors that may influence their treatment outcomes over a year, such as mood changes and specific blood markers. Participants will go through a thorough screening process, which includes an interview and a blood test, to help with diagnosis. Families will also be involved in follow-up visits that include various assessments to track the youth's progress.

To be eligible for this study, participants must be between 9 and 19 years old and have a diagnosis of bipolar disorder or a related condition confirmed by the study team. It’s important that they can communicate in English, along with a caregiver who will be involved in their ongoing assessment and treatment. Participants can expect to receive personalized care, including medication management and psychosocial support, while contributing to research that aims to improve treatment methods for bipolar disorders in children and adolescents.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Youth 9-19 years old
• • Youth diagnosed with Bipolar disorder (I, II, Other Specified) or Cyclothymic Disorder by the study team during the diagnostic interview screening
• • Youth is able to read and communicate in English to the degree necessary to be able to assent and participate (with help) in their treatment and assessments appropriate for ages 9 and up
• • Youth has a caregiver able to participate in ongoing basis in assessment and treatment
• • The participating caregiver can reliably read and communicate in English for purposes of study consenting, assessment, and treatment, unless preferred language translation services are regularly available.
• Exclusion Criteria:
• • Youth has DSM-5 diagnosis of autism spectrum disorder
• • Youth has DSM-5 diagnosis of substance or alcohol abuse with impairment within 3 mos.
• • Youth has a medical or psychiatric disorder that is life-threatening or requires immediate hospitalization or emergency medical or therapeutic treatment
• • Evidence of recent sexual or physical abuse of the youth by legally responsible caregivers
• • Evidence of recent intimate partner violence between caregivers responsible for the youth's care