Study of Safety and Efficacy of a Probiotic and Postbiotic in Overweight Individuals

Launched by THE ARCHER-DANIELS-MIDLAND COMPANY · Jun 20, 2022

Keywords

ClinConnect Summary

This clinical trial is looking into the effects of a probiotic (which are live bacteria that can help your gut health) and a postbiotic (which are heat-treated bacteria) on overweight individuals. The researchers want to find out if these products can help with weight management and overall health for people who have a body mass index (BMI) between 25 and 33, and who have abdominal obesity.

To be eligible for the study, participants should be between 18 and 70 years old and have a waist measurement of over 85 cm for females or over 90 cm for males. However, there are some important criteria to consider. For example, people who have taken certain medications in the month before the study, or those who have specific health conditions like diabetes or gastrointestinal diseases, may not be able to participate. If you join the study, you can expect to be part of a program that involves monitoring and support to help understand how these probiotics and postbiotics can affect your health. It's a chance to contribute to research that could benefit many others facing similar challenges.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Body mass index 25-33kg/m2
• • Abdominal obesity (female waist circumference\>85cm; male waist circumference\>90cm)
• • written informed consent
• Exclusion Criteria:
• • Taking the following medication within 1 month before starting the study: appetite stimulants/suppressants, lipid lowering drug, contraceptive
• • taking antibiotics within 2 months before starting the study
• • secondary obesity or secondary hypertension, diabetes type 1, GI disease, dyslipidaemia, type 2diabetes, hypertension
• • consumption of pre- and probiotic-enriched products or dietary supplement for at least 4 weeks prior to the first screening visit
• • nicotine, drug or alcohol abuse,
• • other condition that, in the opinion of the investigators, would make participation not in the best interest of the patient or could prevent, limit or confound the Study's results