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Search / Trial NCT05429827

The Therapeutic Effects of Dextrose Injection for Myofascial Pain Syndrome

Launched by NATIONAL CHENG-KUNG UNIVERSITY HOSPITAL · Jun 22, 2022

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Myofascial Trigger Point Endplate Noise Dextrose.

ClinConnect Summary

This clinical trial is studying the effects of dextrose injections on patients with myofascial pain syndrome, particularly focusing on a condition called myofascial trigger point pain in the upper trapezius muscle (located in the neck and upper back). Participants will be divided into three groups: one group will receive a saltwater solution (normal saline), while the other two groups will receive different concentrations of dextrose (a type of sugar) to see how these injections help reduce pain and improve muscle function over time.

To be eligible for this trial, participants must be at least 20 years old, able to communicate clearly, and have been experiencing myofascial pain for more than three weeks with a specific tender point in their upper back. However, individuals with serious medical issues, certain bleeding disorders, or specific health conditions like diabetes or pregnancy cannot participate. Throughout the study, participants can expect to receive their assigned injection and then be monitored for changes in their pain and muscle condition at various points: one hour, one week, two weeks, and one month after the injection. This research aims to better understand how different types of dextrose injections might help alleviate myofascial pain.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1). Patients should be 20 years of age or older;
  • 2). They are able to communicate freely;
  • * 3). Patients have the diagnosis of myofascial pain syndrome (MPS) with a definite myofascial trigger point (MTrP) in the neck base and upper back regions (the upper trapezius muscle). The MTrP is identified based on the following criteria, as recommended by Simons \[Simons et al., 1999\]:
  • (a). a localized tender spot in a palpable taut band of muscle fibers,
  • (b). recognized pain (as the usual clinical complaint) when the tender spot is compressed,
  • (c). characteristic and consistent referred pain.
  • 4). Symptoms of MPS should be more than 3 weeks.
  • Exclusion Criteria:
  • (1). acute or serious medical problems;
  • (2). cognitive impairment or psychiatric disorder;
  • (3). coagulopathy or any other bleeding disorder;
  • (4). taking medication of anticoagulation or antithrombolytics;
  • (5). sensory deficiency over the body part where MTrPs located;
  • (6). serum hepatitis B or acquired immunodeficiency syndrome;
  • (7). malignancy;
  • (8). pregnant or likely to be pregnant.
  • (9). diabetes mellitus

About National Cheng Kung University Hospital

National Cheng Kung University Hospital is a leading academic medical institution in Taiwan, dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its extensive resources and expertise in various medical fields to facilitate groundbreaking studies that enhance patient care and medical knowledge. Committed to adhering to the highest ethical standards and regulatory guidelines, National Cheng Kung University Hospital fosters collaborations with researchers, healthcare professionals, and industry partners to drive the development of new therapies and improve health outcomes for diverse populations.

Locations

Tainan, , Taiwan

Patients applied

0 patients applied

Trial Officials

Ta-Shen Kuan, M.D., M.S.

Principal Investigator

National Cheng-Kung University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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