Glucose Monitoring After Acute Myocardial Infarct in People With Diabetes

Launched by IMPERIAL COLLEGE LONDON · Jun 21, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how continuous glucose monitors, specifically the Dexcom ONE model, can help people with type 2 diabetes manage their blood sugar levels after experiencing a heart attack (also known as an acute myocardial infarction). The goal is to see if using these devices can keep blood sugar levels within a healthy range over six months and whether this might lead to better outcomes, like reducing the risk of death or serious heart problems.

To participate in the study, you need to be an adult over 18 years old with type 2 diabetes, and you should have been admitted to the hospital due to a heart condition. You must also be taking medications to control your blood sugar. However, some people may not be eligible, such as those with very good blood sugar control or those who have had certain surgeries. If you join, you can expect to wear a glucose monitor for six months, which will help track your blood sugar levels continuously. This trial is important because it may help improve care for people with diabetes who have had heart issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• From the Hammersmith Hospital In-patient Cardiology Services:
• • Adults aged \>18 years
• • Known or newly diagnosed type 2 diabetes
• • Taking one or more oral hypoglycaemic agent, GLP1 receptor analogue and/or insulin
• • Admitted to Hammersmith Hospital cardiology inpatient services with ACS
• • Raised blood troponin level on admission
• From Imperial College Healthcare Trust Diabetes and Cardiology Clinics:
• • Adults aged \>18 years
• • Known type 2 diabetes
• • Previous acute coronary syndrome within the last 10 years but \> 6 months ago
• • Taking one or more oral hypoglycaemic agent and /or GLP1 receptor analogue, and/or insulin
• Exclusion Criteria:
• From the Hammersmith Hospital In-patient Cardiology Services:
• • HbA1c \<48mmol/mol
• • People who have previously had bariatric surgery
• • People taking hydroxyurea
• • People who undergo haemodialysis or peritoneal dialysis
• • Unable to participate due to other factors, as assessed by the Chief Investigators
• • Pregnancy as determined by clinical team
• • Known to have a terminal condition or conditions that suggest a life expectancy less than 1 year
• From Imperial College Healthcare Trust Diabetes and Cardiology Clinics:
• • HbA1c \<48mmol/mol
• • People who have previously had bariatric surgery
• • People taking hydroxyurea
• • People who undergo haemodialysis or peritoneal dialysis
• • Unable to participate due to other factors, as assessed by the Chief Investigators
• • Pregnancy as determined by clinical team
• • Known to have a terminal condition or conditions that suggest a life expectancy less than 1 year
• • Previous acute coronary syndrome more than 10 years ago or within the last 6 months
• • Withdrawal criteria
• • The subject has a serious event related to the study
• • Investigated initiated discontinuation of study due to participation or equipment concerns
• • Withdrawal of consent