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Search / Trial NCT05433467

CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

Launched by NORTHERN JIANGSU PEOPLE'S HOSPITAL · Jun 21, 2022

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Cirrhosis Hepatocellular Carcinoma Localization Needle

ClinConnect Summary

This clinical trial is looking at a new way to locate tiny liver tumors called micro hepatocellular carcinoma before surgery. These tumors are less than 1 centimeter in size and can be tricky to find using standard imaging methods like CT scans or ultrasounds. By using specialized CT guidance, doctors hope to improve the accuracy of the surgery, which could lead to shorter surgery times and less bleeding during the procedure.

To participate in this study, you need to be at least 18 years old and have a diagnosis of liver cirrhosis, along with a small tumor that hasn’t been easily located by regular imaging. However, certain health conditions, like severe liver disease or uncontrolled high blood pressure, may prevent you from joining. If eligible, participants can expect to undergo advanced imaging techniques to help pinpoint the tumor before surgery, which may lead to better outcomes. The trial is currently recruiting participants of all genders and is looking for volunteers within the age range of 18 and older.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Be at least 18 years old and give informed consent to participate in the study
  • 2. A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause.
  • 3. micro hepatocellular carcinoma (diameter less than 1cm).
  • 4. Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion.
  • 5. Preoperative CT enhancement or MRI can detect the lesion.
  • Exclusion Criteria:
  • 1. Child-Pugh grade C
  • 2. Uncontrolled Hypertension
  • 3. Severe lung dysfunction
  • 4. Severe cardiac dysfunction

About Northern Jiangsu People's Hospital

Northern Jiangsu People's Hospital is a leading healthcare institution dedicated to advancing medical research and improving patient outcomes. Located in Northern Jiangsu, China, the hospital is renowned for its comprehensive clinical services and commitment to innovative medical practices. As a clinical trial sponsor, the hospital collaborates with a multidisciplinary team of healthcare professionals and researchers to conduct rigorous studies aimed at evaluating new treatments and interventions. With a focus on patient safety and ethical standards, Northern Jiangsu People's Hospital strives to contribute to the global medical community by enhancing evidence-based practices and fostering advancements in healthcare.

Locations

Yangzhou, Jiangsu, China

Patients applied

0 patients applied

Trial Officials

Guo-Qing Jiang, MD

Study Chair

Clinical Medical College, Yangzhou University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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