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Search / Trial NCT05434130

Modulating Exercise Dosage to Improve Concussion Recovery

Launched by UNIVERSITY OF COLORADO, DENVER · Jun 21, 2022

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Intervention Mild Traumatic Brain Injury

ClinConnect Summary

This clinical trial is studying how a specific exercise program can help young people recover from concussions more effectively. Researchers want to find out if a high dose of aerobic exercise, done safely and started within two weeks after a concussion, can help reduce symptoms like headaches, anxiety, and depression faster than the usual treatment. The goal is to create better guidelines for rehabilitation and understand how exercise affects brain function in adolescents who have had a concussion.

To participate in this study, you need to be between 13 and 18 years old and have a concussion diagnosed by a sports medicine doctor, with a symptom score indicating you are still experiencing issues. However, if you have certain neurological disorders, can't exercise for medical reasons, or had a concussion more than six months ago, you won't be eligible. If you join the trial, you can expect to follow a specific exercise program and contribute to important research that could help others recover from concussions in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 13-18 years of age
  • Post-Concussion Symptom Scale (PCSS) score \>10 to ensure participants are not recovered by enrollment
  • Concussion diagnosis by a sports medicine physician
  • Exclusion Criteria:
  • Pre-existing neurological disorders
  • Exercise contraindications
  • Concussion \<6 months before enrollment (excluding the current injury)

About University Of Colorado, Denver

The University of Colorado, Denver, is a leading academic institution dedicated to advancing medical research and improving healthcare outcomes. With a strong emphasis on innovation and collaboration, the university conducts a diverse range of clinical trials aimed at addressing critical health challenges. Its research initiatives are supported by a multidisciplinary team of experts, state-of-the-art facilities, and a commitment to ethical standards and patient safety. By fostering partnerships with local and global communities, the University of Colorado, Denver, strives to translate scientific discoveries into meaningful advancements in clinical practice and public health.

Locations

Aurora, Colorado, United States

Boston, Massachusetts, United States

Cambridge, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

David R Howell, PhD

Principal Investigator

University of Colorado Denver | Anschutz

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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