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Search / Trial NCT05434325

TESTING -ON Post-Trial ObservatioNal Cohort Study

Launched by THE GEORGE INSTITUTE · Jun 21, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Kidney

ClinConnect Summary

The TESTING -ON study is looking at the long-term effects of a medication called oral methylprednisolone on patients with certain kidney diseases, including IgA Nephropathy and End Stage Kidney Disease (ESKD). This study is important because it will help researchers understand how different doses of the medication, and factors like ethnicity and kidney function, can affect patients over time. The trial is currently recruiting participants who were part of the earlier TESTING trial, specifically those who did not experience kidney failure, death, or withdraw their consent during that study.

If you or a loved one is interested in participating, you should be between the ages of 65 and 74 or between 36 and 524 years old, and you must have been part of the previous TESTING trial. Participants in this study can expect to contribute to valuable research that could improve treatment options for kidney diseases in the future. It’s a great opportunity to help others while also learning more about your own health and treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1) Only participants who were randomised into the TESTING trial
  • Exclusion Criteria
  • 1. Participants who have reached kidney failure requiring maintenance dialysis or kidney transplantation during the TESTING trial
  • 2. Participants who died during the TESTING trial
  • 3. Participants who had withdrawn their consent during the TESTING trial
  • 4. Participants who are unable to provide consent for some other reason

About The George Institute

The George Institute for Global Health is a leading research organization dedicated to improving health outcomes through innovative clinical trials and groundbreaking research. Based in Australia, the institute focuses on addressing major health challenges, particularly in the areas of chronic diseases, cardiovascular health, and health equity. With a commitment to translating scientific discoveries into real-world applications, The George Institute collaborates with global partners to advance knowledge and implement effective health interventions. Its multidisciplinary team of researchers employs rigorous methodologies to ensure high-quality evidence that informs policy and practice, ultimately striving to enhance public health on a global scale.

Locations

Adelaide, South Australia, Australia

Toronto, Ontario, Canada

London, Ontario, Canada

St Leonards, New South Wales, Australia

Kingswood, New South Wales, Australia

Montreal, Quebec, Canada

Melbourne, Victoria, Australia

Edmonton, Alberta, Canada

Beijing, , China

Guangzhou, Guangdong, China

Jinan, Shandong, China

Chengdu, Sichuan, China

Beijing, , China

Jinan, Shandong, China

Johor Bahru, Johor, Malaysia

Beijing, Beijing, China

Shenzhen, Guangdong, China

Beijing, Beijing, China

Zhengzhou, Henan, China

Kowloon, , Hong Kong

Ipoh, Perak, Malaysia

Zhengzhou, Henan, China

Shijiazhuang, , China

Shengyang, Liaoning, China

Calgary, Alberta, Canada

Vancouver, British Columbia, Canada

Hamiliton, Ontario, Canada

Toronto, Ontario, Canada

Beijing, Beijing, China

Guangzhou, Guangdong, China

Shijiazhuang, Hebei, China

Shijiazhuang, Hebei, China

Luoyang, Henan, China

Wuhan, Hubei, China

Wuhan, Hubei, China

Wuhan, Hubei, China

Baotou, Inner Mongolia, China

Nanjing, Jiangsu, China

Changchun, Jilin, China

Dalian, Liaoning, China

Jinan, Shandong, China

Jinan, Shandong, China

Taiyuan, Shanxi, China

Chengdu, Sichuan, China

Hangzhou, Zhejiang, China

Hangzhou, Zhejiang, China

Ningbo, Zhejiang, China

Sangzhou, Zhejiang, China

Beijing, , China

Chongqing, , China

Shanghai, , China

Shanghai, , China

Hyderabad, Andhra Pradesh, India

Kozhikode, Kerala, India

Chandigarh, Punjab, India

Chen, Tamil Nadu, India

Lucknow, Uttar Pradesh, India

Kuala Lumpur, Kulala Lumpur, Malaysia

Seremban, Negri Seremban, Malaysia

Kuching, Samarahan, Malaysia

Kuala Lumpur, , Malaysia

Wuhan, Hubei, China

Beijing, , China

Hohhot, Neimenggu, China

Hyderabad, Andhra Pradesh, India

Taiyuan, Shanxi, China

Patients applied

0 patients applied

Trial Officials

Hong Zhang, Prof

Study Chair

Peking University Institute of Nephrology

Vlado Perkovic, Prof

Study Chair

University of New South Wales

Muh Geot Wong, Dr

Principal Investigator

University of New Souht Wales

Jicheng Lv

Principal Investigator

Peking University of Nephrology

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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