Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

Launched by REGIONSHOSPITALET SILKEBORG · Jun 27, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a treatment for Dupuytren's contracture, a condition that causes the fingers to bend toward the palm due to thickened tissue. Researchers want to compare two approaches: one that uses a special needle to loosen the tight tissue (called percutaneous needle fasciotomy) and another that combines this procedure with a corticosteroid injection. The goal is to see which method is more effective in helping people regain movement in their fingers.

To participate in this study, individuals should be between 16 and 99 years old and have Dupuytren's contracture that causes at least 20 degrees of bending in their finger joints. Participants will undergo the treatment, and their progress will be monitored. It's important to note that certain conditions may prevent someone from joining, such as previous hand surgeries or certain medical issues. Overall, this trial aims to find better ways to treat Dupuytren's contracture and improve patients' quality of life.

Gender

ALL

Eligibility criteria

• • Sufficient correction of metacarpophalangeal (MCP) joint during the PNF treatment, defined as \<20° passive extension deficit (PED), is a prerequisite for inclusion.
• Inclusion Criteria:
• • Dupuytren contracture (DC) of ≥ 20° PED in MCP joint measured with a goniometer
• • DC of either II-V finger
• • Well-defined/palpable cord
• Exclusion Criteria:
• • Legally incapacitated
• • Previous study inclusion with another finger ray
• • Isolated proximal interphalangeal (PIP) or distal interphalangeal (DIP) joint contracture, defined as MCP joint contracture \< 20° PED regardless of the deficit in the PIP or DIP joint
• • Previous hand surgery of the affected finger for any reason
• • Known allergy to the study medication
• • Anticoagulant therapy (Acetylsalicylic acid is NOT an exclusion criterion)
• • Pregnant or lactation
• • Insulin dependent diabetes mellitus
• • Ongoing systemic infection or local infection at the site of the procedure
• • Rheumatoid arthritis
• • Amyloidosis or mucopolysaccharidosis
• • Unable to communicate, cooperate or participate in follow-up