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Evaluation of Clinical Outcomes of Unruptured bAVMs Treated With Medical Management Alone Based on Multimodal CT

Launched by BEIJING TIANTAN HOSPITAL · Jul 4, 2022

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Unruptured Arteriovenous Malformations Multimodal Ct Machine Learning

ClinConnect Summary

This clinical trial is studying the outcomes of patients with unruptured brain arteriovenous malformations (bAVMs) who are being treated with medical management only, using advanced imaging techniques called multimodal CT scans. The goal is to understand how the characteristics of these bAVMs, such as their structure and blood flow patterns, can help predict various health outcomes, like the risk of bleeding, new seizures, or other neurological problems. Researchers will closely monitor patients over three years to gather important information about these conditions.

To participate in this study, individuals must have a confirmed diagnosis of bAVMs and no history of bleeding related to them. They should not have had any previous treatments or any other specific types of vascular issues. Participants will undergo regular follow-ups at six months, one year, two years, and three years to track their health and any changes in their condition. This study is actively recruiting participants of all genders, and it aims to improve our understanding of how to manage and treat brain arteriovenous malformations effectively.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients with confirmed diagnosis of brain arteriovenous malformations in the brain, basal ganglia, thalamus, corpus callosum, cerebellum and other locations.
  • 2. Patients with no history of previous arteriovenous malformation-related hemorrhage and no arteriovenous malformation-related hemorrhage confirmed by CT examination.
  • 3. Patients with Radiographic examinations completed without any treatment
  • Exclusion Criteria:
  • 1. Patients with simple arteriovenous fistula.
  • 2. Patients with combined dural arteriovenous fistulas.
  • 3. Arteriovenous malformations occurring in the spinal cord.
  • 4. Pregnant patients were not included in this study.

About Beijing Tiantan Hospital

Beijing Tiantan Hospital, affiliated with Capital Medical University, is a leading medical institution in China renowned for its expertise in neurology, neurosurgery, and various other specialties. As a prominent clinical trial sponsor, the hospital is committed to advancing medical research and improving patient outcomes through innovative studies. With a focus on high-quality clinical trials, Beijing Tiantan Hospital adheres to rigorous ethical standards and regulatory requirements, fostering collaboration with academic institutions and industry partners to facilitate the development of cutting-edge therapies and interventions. Its state-of-the-art facilities and experienced research team enable the hospital to play a pivotal role in the global medical research landscape.

Locations

Zhengzhou, Henan, China

Nanjing, Jiangsu, China

Beijing, Beijing, China

Zhengzhou, Hennan, China

Beijing, Beijing, China

Patients applied

0 patients applied

Trial Officials

Dong Zhang, Doctor

Study Chair

Beijing Tiantan Hospital, Beijing Hospital

Shaosen Zhang, Doctor

Study Director

Beijing Tiantan Hospital

Guosheng Zhou

Principal Investigator

The First Affiliated Hospital of Zhengzhou University

Yongbo Yang

Principal Investigator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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