Vitamin D for Critically Traumatic Patients

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Jul 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how high doses of vitamin D can help critically injured patients recover better and potentially reduce their chances of dying from severe trauma. Trauma is a major health issue, especially in Taiwan, where it is a leading cause of death for younger people. The researchers want to find out if giving patients multiple high doses of vitamin D within one week can improve their health outcomes. They will measure certain vitamin D levels in the blood at various times before and after treatment to see how it affects recovery.

To be eligible for this study, participants need to be adults over 20 years old who have experienced serious injuries and are admitted to the Intensive Care Unit (ICU). However, some individuals won't be able to participate, such as those with chronic liver disease or specific cancer-related conditions. If someone qualifies, they can expect to receive high doses of vitamin D and will be monitored closely during their recovery to gather important information on the effects of the treatment. This trial is currently recruiting participants, and all genders are welcome to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Major trauma adult (\> 20 years old) with Injury Severity Score equal or higher than 9, who is admitted to ICU
• Exclusion Criteria:
• Patients with the following conditions:
• • Chronic liver disease
• • Contraindication to enteral feeds
• • Hypercalcemia
• • Current use of vitamin D, estrogen, or medications for bone disease
• • High risk of hypercalcemia, ex. metastatic cancer, primary hyperparathyroidism, sarcoidosis, multiple myeloma