Multiomics Biomarkers for Urolithiasis

Launched by CHINESE UNIVERSITY OF HONG KONG · Jul 7, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at a condition called urolithiasis, which is the formation of urinary stones that can cause pain and other issues. The goal of the study is to compare urine samples from patients who have had recurrent urinary stones to those who have never had them. Researchers want to identify specific markers in the urine that might help predict which patients are likely to have stones return after treatment.

To participate in this study, individuals must be at least 18 years old and have a history of recurrent urinary stones, meaning they have had more than two episodes of stones. There is also a control group for people without any history of urinary stones. Participants can expect to provide urine samples for analysis and help researchers understand more about why some people develop stones repeatedly while others do not. It's important to note that those with active urinary infections or certain types of stones will not be eligible for the study. The trial is currently recruiting participants, so if you meet the criteria and are interested, you can reach out for more information.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with history of recurrent urinary stone
• • Age greater than or equal to 18 years old
• • Have more than 2 episodes of radio-opaque stone disease (bilateral stones were counted as two episode)
• • Patients with no history of urinary stone disease
• • Age greater than or equal to 18 years old
• • With no history of urinary calculi, from history and imaging.
• Exclusion criteria:
• • Patient refused or unable to provide consent for the study
• • Patient with active urinary infection
• • Patient with radiolucent stone or infective stone
• • Patients with no history of urinary stone disease (for control group)
• • Patient refused or unable to provide consent for the study
• • Patient with active urinary infection