Post-radiotherapy Rhinosinusitis in Children

Launched by UNIVERSITY HOSPITAL, LILLE · Jul 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying chronic rhinosinusitis (CRS), a condition that can occur in children who have received radiotherapy for cancer in the face or neck. CRS can cause ongoing sinus problems, and while many children may have changes seen on scans, they might not always show noticeable symptoms. The goal of the study is to find out how common CRS is in children treated for head and neck cancer, how it changes over time, and whether these children need special follow-up care for their sinus issues.

To participate in this study, children must be under 18 years old and have been treated for a head or neck cancer between January 2018 and December 2024. There is also a control group of children with non-head and neck cancers for comparison. Participants will be asked to complete a questionnaire to assess how CRS affects their daily life. This research is important because it will help doctors understand the long-term effects of cancer treatment on children's sinus health and determine the need for ongoing care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Study population: all patients under 18 years of age managed for a head neck mesenchymal cancer between January 1, 2018 and December 31, 2024
• • Control population: all patient under 1 years of age managed for non -head neck mesenchymal cancer between January 1, 2018 and December 31, 2024
• Exclusion Criteria:
• • Patients with hematological tumors;
• • Patients with mucociliary pathologies or proven allergic rhinitis before the diagnosis of cancer
• • Patients who have required surgical treatment that has removed more than half of the sinus cavities
• • Tumor recurrence at the time of inclusion
• • Sinus surgery between the last radiological check-up and inclusion
• • Administrative reasons: inability to receive informed information.