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Search / Trial NCT05456581

Scotoma Perimetry Oculomotor Training

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Jul 12, 2022

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Plasticity Central Vision Loss

ClinConnect Summary

This clinical trial, called Scotoma Perimetry Oculomotor Training, is studying new ways to help people with severe vision loss due to conditions like macular degeneration. The goal is to understand how the brain can adapt after losing central vision, which could lead to better treatment options for those affected. This research is particularly important for older adults, as many experience declines in vision that affect their daily lives.

If you or a loved one is between the ages of 65 and 74 and has significantly impaired vision (20/100 or worse) from macular degeneration for at least two years, you might be eligible to participate. Participants will undergo training sessions that focus on improving visual function. However, it's important to know that individuals who have difficulty sitting still for long periods or have very large areas of vision loss may not qualify. This trial could offer valuable insights into improving sight for many people experiencing low vision challenges.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Severely impaired vision in both eyes (20/100 or worse)
  • Diagnosis of Macular Degeneration
  • Light sensitivity in the macular retina that is at least 10 dB units worse than in peripheral regions, as demonstrated by a scanning laser ophthalmoscope (SLO, MAIA)
  • Medical record review indicates this disease severity level has been present for at least 2 years.
  • Exclusion Criteria:
  • Inability to sit still in eye tracker for extended periods
  • Inability to visualize iris on video eye tracker
  • Bilateral retinal scotomas larger than 20° diameter

About University Of Alabama At Birmingham

The University of Alabama at Birmingham (UAB) is a prominent academic institution and research hub dedicated to advancing healthcare through innovative clinical trials. Renowned for its commitment to medical discovery and education, UAB conducts cutting-edge research across a wide array of disciplines, including oncology, cardiology, neurology, and public health. With a robust infrastructure for clinical research, UAB fosters collaboration among interdisciplinary teams, leveraging state-of-the-art facilities and resources to enhance the translation of scientific findings into effective treatments and interventions. As a leader in clinical research, UAB aims to improve patient outcomes and contribute to the broader medical community through rigorous trial design and implementation.

Locations

Birmingham, Alabama, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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