Obstructive Sleep Apnea Treatment in Serious Mental Illness

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Jul 8, 2022

Keywords

ClinConnect Summary

This clinical trial is looking into how treating obstructive sleep apnea (OSA) can help people with serious mental illnesses like schizophrenia, schizoaffective disorder, and bipolar disorder. Many adults with these conditions also struggle with sleep problems, but they often don’t get the help they need. The study aims to see how well people accept OSA treatments and how these treatments might improve their thinking and memory skills.

To participate in this trial, you need to be between 40 and 70 years old and either have a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder, or be a control participant without a major psychiatric illness. You should also be at risk for or diagnosed with obstructive sleep apnea. If you join, you can expect to learn more about your sleep health and possibly receive treatment that could improve your overall well-being. Keep in mind that the trial is not yet recruiting participants, so it will be a little while before you can sign up.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Control participants:
• • lifetime absence of major psychiatric illness
• • 40 to 70 years old
• • be at risk for or have a diagnosis of obstructive sleep apnea
• For participants with serious mental illness:
• • diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder
• • must not be conservatized
• • 40 - 70 years old
• • be at risk or have a diagnosis of obstructive sleep apnea.
• Exclusion Criteria:
• • DSM-IV-TR diagnosis of active alcohol or other substance abuse or dependence in the 3 months preceding enrollment. This will be self-report.
• • Diagnosis of dementia, mental retardation, or other neurological or medical conditions known to affect neurophysiologic or neurocognitive functioning, or autoimmune disease
• • Other major DSM-IV-TR Axis I Disorder
• • Medical problems that interfere with a participant's ability to complete the assessments
• • Plans to move out of the San Diego county area within the following 6 months
• • Diagnosis of OSA and currently receiving APAP, CPAP, or any treatment from a physician.