Inspiratory Muscle Strength Training in Adults With Obesity

Launched by FLORIDA STATE UNIVERSITY · Jul 13, 2022

Keywords

ClinConnect Summary

This clinical trial is studying whether a specific type of exercise called inspiratory muscle strength training can help lower blood pressure in adults who are obese. The goal is to find out if this training, which focuses on strengthening the muscles used for breathing, can lead to better health outcomes for individuals with obesity.

To participate in the study, individuals should have a body mass index (BMI) between 30 and 40, which indicates obesity. However, there are some conditions that may exclude someone from joining, such as having significant heart or lung problems, recent weight changes, or certain other health issues. Participants can expect to engage in breathing exercises and will be monitored throughout the trial. This study is currently recruiting participants of all genders between the ages of 18 and 65, and it aims to contribute valuable information about managing blood pressure in people with obesity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Body mass index 30 - 40 kg/m2
• Exclusion Criteria:
• • Not weight stable (\<5% change in body mass over the past six months)
• • Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
• • Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted)
• • Diagnosed obstructive sleep apnea
• • Previous bariatric surgery
• • Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
• • Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
• • Pregnant (self-reported and confirmed via urine pregnancy test), lactating (self-reported), or post-menopausal (self-reported) females
• • Prisoners
• * Per the POWERbreathe® company:
• • Patients who have undergone recent abdominal surgery and those with abdominal hernia.
• • Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnea.
• • If a patient is suffering from a ruptured eardrum or any other condition of the ear.
• • Patients with marked elevated left ventricular end-diastolic volume and pressure.
• • Patients with worsening heart failure signs and symptoms after training.
• • If an individual is suffering from a cold, sinusitis or respiratory tract infection, it is advised that they do not use the POWERbreathe device.