Preoperative Silicone Ointment and Wound Healing
Launched by YALE UNIVERSITY · Jul 12, 2022
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Following surgical procedures, the formation of hypertrophic scars and keloids affects patients' well-being, including quality of life and mental/psychological health. Scars in certain areas, including the face, neck, ears, and upper chest and back, are especially likely to develop abnormally. Due to these adverse outcomes, patients often request products and procedures that will improve the appearance of scars. Few studies have addressed preoperative measures that can improve scar healing.
Surgeons often recommend that patients apply moisturizing ointments to the area of the incision prio...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Scheduled to undergo non-emergent surgery of the head and/or neck for a benign (non-cancerous) condition
- • Able to comply with all study procedures for the duration of the study
- • Provision of signed and dated informed consent form
- Exclusion Criteria:
- • Current use of products intended to improve scar healing (silicone or otherwise); skincare products not specifically marketed for scar healing are acceptable
- • Known allergic reactions to components of the silicone ointment
- • Dermatologic conditions that disrupt the integrity of the skin, e.g. severe acne, psoriasis
- • Need for tracheostomy postoperatively
- • Have any form of active malignancy at the time of surgery
- • Have a history of radiation involving the surgical site
- • Prior surgery involving all or part of the planned surgical incision
- • Current use of chronic steroids or other immunosuppressive medications
- • Lack of decision-making capacity
- • Not fluent in English
About Yale University
Yale University, a prestigious Ivy League institution located in New Haven, Connecticut, is renowned for its commitment to advancing medical research and clinical innovation. With a rich history of academic excellence and a robust infrastructure for scientific inquiry, Yale serves as a leading sponsor for clinical trials aimed at improving patient care and developing new therapeutic approaches. The university's multidisciplinary teams of researchers and clinicians collaborate to conduct rigorous and ethical studies, leveraging cutting-edge technologies and methodologies to address critical health challenges. Through its dedication to fostering an environment of inquiry and discovery, Yale University plays a pivotal role in translating research findings into clinical practice, ultimately enhancing health outcomes for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
New Haven, Connecticut, United States
Patients applied
Trial Officials
Yan Lee, MD
Principal Investigator
Yale University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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