Normal Reference Range for Neonatal Echocardiography

Launched by CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY · Jul 14, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on understanding normal heart function in newborns through a test called echocardiography, which uses sound waves to create images of the heart. The goal is to establish a standard range of measurements for healthy newborns, especially those who are premature. Currently, there are no consistent guidelines for evaluating the hearts of newborns, and this study aims to fill that gap. By doing so, healthcare providers can better identify and treat heart problems in critically ill newborns.

To participate in this trial, babies must be between 1 and 28 days old, have a gestational age of over 30 weeks, and weigh more than 1250 grams at birth. They should not have serious health issues like congenital heart disease or certain infections. Parents who agree to have their babies take part will help researchers gather important information that can improve care for newborns with heart conditions. This study is actively recruiting participants, and all families will be fully informed about the process and what to expect.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Outpatient or inpatient neonate
• • Gestational age \> 30weeks and birthweight \> 1250 grams
• • Appropriate for gestational age
• • Without perinatal asphyxia
• • Without skin lesion on the left chest wall
• • with family informed consent for neonatal echocardiography
• Exclusion Criteria:
• • specialist cardiac ultrasound suggests congenital heart disease;
• • PDA with hemodynamic abnormalities, defined as: PDA \> 1.5 mm (left-to-right shunt) and left atrial diameter/aortic root \> 1.5 or the need for the use of inotropes;
• • invasive mechanical ventilation therapy,
• • non-invasive mechanical ventilation with FiO2 \>0.3
• • major anomalies
• • blood culture-proven neonatal sepsis
• • persistent pulmonary hypertension
• • renal failure
• • necrotizing enterocolitis ≥ stage II
• • post surgery
• • Maternal history of severe anemia, or prenatal massive bleeding