Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

Launched by WOMEN AND INFANTS HOSPITAL OF RHODE ISLAND · Jul 14, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the best way to treat iron-deficiency anemia in pregnant women. Iron deficiency anemia means that a person does not have enough iron in their body, which is crucial for making healthy red blood cells. In this trial, researchers are comparing two methods of treatment: intravenous (IV) iron, which is given through a vein, and oral iron, which is taken by mouth. The goal is to see whether IV iron is more effective and safer in helping mothers and their babies, especially in preventing severe complications during childbirth and improving the baby's development.

To participate in this study, women must be between 18 and 45 years old, pregnant with a single baby, and diagnosed with moderate to severe iron-deficiency anemia. They should be between 13 to 30 weeks along in their pregnancy and plan to give birth at a participating hospital. Participants can expect to receive either IV iron or oral iron and will be closely monitored throughout the trial. This study is currently recruiting participants, and it’s important for interested individuals to discuss their eligibility and any questions with their healthcare provider.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pregnant women between the ages of 18-45
• • Singleton gestation
• • Iron-deficiency anemia (serum ferritin \<30ng/mL and Hb\<11 g/dL)
• • At 13-30 weeks gestation
• • Plan to deliver at participating hospital
• Exclusion Criteria:
• • Non-iron-deficiency anemia e.g thalassemia, sickle cell disease, B12 or folate deficiency, hypersplenism.
• • Malabsorptive syndrome, inflammatory bowel disease, gastric bypass, or sensitivity to oral or IV iron
• • Multiple gestation
• • Inability or unwillingness to provide informed consent
• • Inability to communicate with members of the study team, despite the presence of an interpreter
• • Planned delivery at a non-study affiliated hospital