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Correlation Between Various Urinary Exosomal Protein Biomarkers and Pathological Manifestation in Thyroid Follicular Neoplasm: Early and Pre-operative Diagnosis of Follicular Thyroid Cancer

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Jul 14, 2022

Trial Information

Current as of September 10, 2025

Recruiting

Keywords

Exosome Urine Biological Marker Thyroglobulin Galactin 3

ClinConnect Summary

This clinical trial is studying how certain proteins found in urine might help doctors diagnose follicular thyroid cancer earlier and more accurately before surgery. Thyroid cancer is common, and while some types can be identified through special tests, follicular thyroid cancer is more challenging to diagnose because it often requires surgery for a definitive answer. The researchers hope that by looking at these specific proteins in urine, they can improve the way doctors identify this type of cancer before patients undergo surgery.

To participate in this study, patients must have been diagnosed with nodular goiter (enlarged thyroid) or different types of thyroid cancer, including follicular cancer, and they should be preparing for surgery. The trial is currently recruiting participants of all genders, aged between 18 and 75. If you join the study, you will help researchers understand if these urine tests can make diagnosing thyroid cancer easier and could potentially lead to better treatment options in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • diagnosed patients with nodular goiter or multinodular goiter, thyroid papillary, follicular and anaplastic thyroid cancer, pre-operation.
  • Exclusion Criteria:
  • unclearly diagnosed patients with thyroid papillary, follicular and anaplastic thyroid cancer

About National Taiwan University Hospital

National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.

Locations

Taipei, Taiwan

Patients applied

0 patients applied

Trial Officials

CHIH-YUAN WANG, Doctor

Principal Investigator

Department of Internal Medicine, National Taiwan University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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