Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Launched by UNIVERSITY HOSPITAL ULM · Jul 20, 2022
Trial Information
Current as of September 03, 2025
Unknown status
Keywords
ClinConnect Summary
The objective of the PINES project is to identify a model that can accurately predict 1) time to complete neuromuscular recovery, 2) optimal timing and dose of neuromuscular blocking agents at each time point during surgery, and 3) TOF ratio at the estimated end of surgery to assess residual paralysis. Furthermore, a prospective clinical pilot study will be conducted to compare anesthesiologist-predicted neuromuscular recovery with that of the algorithm.
The project consists of two main objectives:
I. Big data analysis
* Establishing a data warehouse: Electronic registry data will be use...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients (≥18 years) undergoing non-cardiac surgery receiving general anesthesia with intraoperative neuromuscular blocking agent administration and available TOF data.
- Exclusion Criteria:
- • none
About University Hospital Ulm
University Hospital Ulm is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical excellence. Affiliated with the University of Ulm in Germany, the hospital integrates cutting-edge medical education, pioneering research initiatives, and comprehensive patient care. With a strong emphasis on interdisciplinary collaboration, University Hospital Ulm actively participates in clinical trials aimed at developing new therapeutic strategies and improving patient outcomes. Its commitment to ethical standards and rigorous scientific methodology positions it as a trusted sponsor in the realm of clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Munich, Bavaria, Germany
Ulm, Baden Württemberg, Germany
Ulm, , Germany
Patients applied
Trial Officials
Manfred Blobner, MD PhD
Principal Investigator
Department of Anesthesiology and Intensive Care Medicine, University of Ulm,Ulm, Germany
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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