iNav-based, Automated Coronary Magnetic Resonance Angiography for the Detection of Coronary Artery Stenosis

Launched by AARHUS UNIVERSITY HOSPITAL · Jul 21, 2022

Keywords

ClinConnect Summary

This clinical trial is testing a new type of heart scan called Magnetic Resonance (MR) angiography, which uses advanced technology to help detect narrowing of the coronary arteries, a condition known as coronary artery stenosis. This narrowing can lead to serious heart problems, including heart attacks. The trial will involve 230 patients who are at risk for heart disease and have been referred for a standard invasive heart procedure. These patients will receive both the new MR scan and the traditional procedure so that researchers can compare the results. The goal is to see if the MR scan can accurately identify problems with the arteries without the risks linked to invasive methods or CT scans.

To be eligible for this trial, participants must be at least 18 years old, have a body mass index (BMI) under 35, and be experiencing stable heart symptoms. They should also be scheduled for a CT scan of the heart within 28 days. However, people who have had certain heart surgeries or who have irregular heartbeats may not qualify. If you join the study, you can expect to undergo both the MR scan and the standard procedure, helping researchers understand if this new method can be a safer and more consistent way to check for heart artery narrowing across different hospitals.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Inclusion Criteria:
• • ≥18 years old
• • Subject has provided informed written consent
• • BMI \< 35
• • Sinus Rhythm
• • Stable symptom at time of inclusion
• • Undergoing CCTA within 28 days
• Exclusion Criteria:
• • Any contraindication to CMR
• • Previous coronary revascularisation
• • Inability to take sublingual nitroglycerin
• • Irregular heart rate