6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension

Launched by GENERAL HOSPITAL OF NINGXIA MEDICAL UNIVERSITY · Jul 26, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at a specific treatment using a fluid called 6% Hydroxyethyl Starch (130/0.4) to help prevent low blood pressure after spinal anesthesia during cesarean sections. The goal is to find out the right amount of this fluid that is effective for keeping blood pressure stable in women undergoing this type of surgery.

To participate in the study, women aged 18 to 40 who are having an elective cesarean section and are in good health (classified as either healthy or with mild health issues) may be eligible. However, there are some important criteria to note: women who are very short, very heavy, or have certain medical conditions, such as high blood pressure or significant blood disorders, cannot take part. If you join the study, you can expect close monitoring and support from the medical team to ensure your safety and well-being throughout the process.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 18-40 years
• • Primipara or multipara
• • Singleton pregnancy ≥ 37 weeks
• • American Society of Anesthesiologists physical status classification I to II
• • Scheduled for elective cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Body height \< 150 cm
• • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
• • Eclampsia or chronic hypertension or baseline blood pressure ≥ 160mmHg
• • Hemoglobin \< 7g/dl
• • Coagulation or renal function disorders
• • Known allergy to hydroxyethyl starch
• • Fetal distress, or known fetal developmental anomaly