EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy

Launched by THE NETHERLANDS CANCER INSTITUTE · Jul 27, 2022

Keywords

ClinConnect Summary

The ENHANCE study is researching a special program designed to prepare patients with bladder cancer for surgery, specifically a procedure called radical cystectomy, which involves removing the bladder. This program includes various activities and support to help improve patients' overall health and well-being before and after their surgery. The study aims to find out if this program can reduce complications, shorten hospital stays, and improve physical fitness, mental health, and quality of life for patients.

To participate in this study, you must be at least 18 years old and have a confirmed diagnosis of bladder cancer. However, if you have serious mental health issues, are scheduled for surgery within the next three weeks, or cannot understand Dutch well enough to follow instructions, you may not be eligible. If you join, you can expect to engage in exercises and receive support that could help you manage your health better during this challenging time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Histologically confirmed, primary, bladder cancer (cTa-4N0/N+M0),
• • Planned to undergo radical cystectomy,
• • Age ≥ 18 years.
• Exclusion Criteria:
• • Subjects with severe cognitive or psychiatric disorders,
• • Subjects who are operated within 3 weeks,
• • Subjects with insufficient command of the Dutch language, which precludes them from following study instructions or completing study questionnaires,
• • Subjects who have contraindications to safely perform exercise training or testing (i.e., CPET),
• • Subject who are unable or unwilling to participate in the intervention.