Lung Ultrasound-guided Hemodynamic Optimization

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Jul 28, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the use of lung ultrasound to help manage fluid levels in patients undergoing certain types of surgery. The goal is to ensure patients receive the right amount of fluid during surgery, which can help prevent complications after the procedure, like organ failure. By using lung ultrasound, doctors can monitor the lungs for signs of fluid overload in real-time, potentially improving patient outcomes compared to standard methods of managing fluid levels.

To participate in this trial, patients must be at least 18 years old and scheduled for abdominal, orthopedic, or vascular surgery that will require general anesthesia. They should have a higher risk of complications based on their health history, as defined by certain medical conditions. Eligible participants can expect to have their lung health monitored during surgery and may benefit from a more personalized approach to fluid management, which could lead to a quicker recovery and shorter hospital stay. It's important for potential participants to understand that this trial aims to enhance patient care and safety during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age\> 18 years old
• • Abdominal, orthopaedic or vascular surgery with general anaesthesia
• • Patient of legal age ≥ 18 years.
• • ASA score ≥ II
• • Estimated duration of surgery \> 2 hours
• • At least two of the following comorbidities (age \> 50 years, hypertension, heart disease, electrocardiogram (ECG) abnormality, acute pulmonary oedema, smoking, stroke, peripheral arterial disease, non-insulin dependent or insulin dependent diabetes, ascites, chronic renal failure)
• • Signed consent.
• • Affiliation to a social security scheme.
• Exclusion Criteria:
• • Severe untreated or unbalanced hypertension on treatment.
• • Preoperative renal failure on dialysis.
• • Acute heart failure.
• • Acute coronary insufficiency.
• • Vascular surgery with renal plasty.
• • Cardiac surgery.
• • Preoperative shock.
• • Refusal of patient participation.
• • Pregnant, parturient or breastfeeding woman.
• • Patient under guardianship or private law.
• • Acute respiratory distress syndrome according to the Berlin definition
• • respiratory distress not fully explained by cardiac failure or increased blood volume,
• • PaO2/FiO2 ratio ≤ 300 mm Hg on mechanical ventilation (invasive or non-invasive)
• • Chronic respiratory failure with home oxygen therapy.
• • Chronic interstitial lung disease
• • Presence of an acoustic barrier (pneumothorax, subcutaneous emphysema, pleural calcifications, chest bandage, gunshot shrapnel...)
• • Participation in other interventional drug research.
• • Surgical fields covering the sites of investigation in lung ultrasound.