Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft

Launched by UNIVERSITY OF LOUISVILLE · Jul 29, 2022

Keywords

ClinConnect Summary

This clinical trial is studying two different types of grafts used during dental procedures to help preserve the jawbone after a tooth extraction. Specifically, researchers want to compare a natural graft made from human tissue (called an allograft) to a synthetic graft made from a material similar to bone (called an alloplast) after four months. Both types of grafts will be covered with a special membrane to help them heal properly. The goal is to see which option works better for preserving the bone structure where a tooth used to be, before placing a dental implant.

To participate in this trial, individuals must be at least 18 years old, healthy enough to undergo the procedure, and need to have one non-molar tooth that requires extraction. They should also have at least one neighboring tooth. However, certain conditions, like specific diseases affecting the jaw or certain medications, may prevent someone from joining the study. Participants will be informed about the study's details and must provide consent before taking part. This trial is currently looking for volunteers, and by joining, participants can contribute to understanding the best ways to support dental health after tooth loss.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Have one non-molar tooth requiring extraction that will be replaced by a dental implant.
• • The site must be bordered by at least one tooth.
• • 2. Healthy male or female who is at least 18 years old.
• • 3. Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.
• Exclusion Criteria:
• • 1. Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
• • 2. Presence or history of osteonecrosis of jaws.
• • 3. Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
• • 4. Patients who have been treated with oral bisphosphonates for more than three years.
• • 5. Patients with an allergy to any material or medication used in the study.
• • 6. Patients who need prophylactic antibiotics
• • 7. Previous head and neck radiation therapy.
• • 8. Chemotherapy in the previous 12 months.
• • 9. Patients on long term NSAID or steroid therapy.
• • 10. Pregnant patients.