VIsual Pathways Model in Neuro-inflammatory Disorders

Launched by UNIVERSITY HOSPITAL, LILLE · Aug 2, 2022

Keywords

ClinConnect Summary

This clinical trial, titled "VIsual Pathways Model in Neuro-inflammatory Disorders," is exploring how certain diseases, like multiple sclerosis (MS) and optic neuritis, affect the nervous system. The researchers aim to understand the damage caused by inflammation in the brain and optic nerve, which can lead to vision problems and other disabilities. By using advanced imaging techniques, they hope to measure the loss of nerve cells and uncover the different ways these diseases progress.

To participate in the trial, individuals must be between 18 and 65 years old and have experienced symptoms of optic neuritis for less than four weeks, confirmed by a specialist. Participants will need to give written consent and be ready to follow the study procedures. Importantly, people with a history of certain eye conditions, diabetes, or those who are pregnant cannot participate. Those who join can expect to undergo various tests and assessments to help researchers gather valuable information that can improve understanding and treatment of neuro-inflammatory disorders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Male or female
• • Aged between 18 and 65 years
• • Presenting a clinical picture of optic neuritis for less than 4 weeks, confirmed by neuro-ophthalmological assessment
• • Patient having given written consent to participate in the study
• • Patient with social insurance
• • Patient willing to comply with all study procedures and duration
• Exclusion Criteria:
• • - history of optic neuritis on the same side as the recent episode for which the patient is being treated
• • history of retinal pathology (retinal detachment, glaucoma, retinopathies, retinal surgery)
• • diabetes
• • chronic alcohol intoxication
• • contraindications to MRI
• • pregnant women
• • persons under protective supervision (ex : guardianship)
• • minors
• • persons deprived of their liberty
• • administrative reasons: inability to receive informed information, inability to participate in the entire study, lack of social security coverage, refusal to sign consent
• • A history of pre-existing CNS inflammatory demyelinating disease is not a criterion for non-inclusion.