DIStal Versus COnventional Radial Access for COMPLEX Large-bore Percutaneous Coronary Intervention

Launched by IGLESIAS JUAN FERNANDO · Aug 4, 2022

Keywords

ClinConnect Summary

The DIStal Versus COnventional Radial Access for COMPLEX Large-bore Percutaneous Coronary Intervention trial, also known as the DISCO RADIAL trial, is studying a new way to access blood vessels during heart procedures. Specifically, it compares using a distal radial artery (located in the wrist) to the traditional radial artery access. Researchers hope that using the distal access will lower the risk of complications, such as blockages in the blood vessel after the procedure. So far, early studies show that this new method is safe and effective, but more research is needed, especially for complex heart conditions.

To participate in this trial, patients should be at least 18 years old and have specific heart issues that require advanced procedures. This includes conditions like chronic total occlusions (where a coronary artery is completely blocked) or heavily calcified lesions. Participants will undergo heart procedures using the new access method, and doctors will closely monitor their progress. It's important to note that some patients, such as those in severe heart conditions or with certain health issues, may not be eligible for this study. Overall, this trial aims to improve heart care and reduce complications for patients requiring complex interventions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years.
• • Patients presenting with CCS or ACS, including unstable angina or NSTEMI.
• • Patients planned for PCI of complex coronary lesions, such as CTO, left main coronary artery disease, heavily calcified lesions, complex bifurcations, or other complex coronary lesions in whom the operator anticipates that a 7F guiding catheter is indicated.
• • Patients able to provide written informed consent.
• Exclusion Criteria:
• • Patients with acute ST-segment elevation myocardial infarction.
• • Patients with cardiogenic shock.
• • Patients on chronic hemodialysis.
• • Patients with contraindications to TRA, such as occlusive upper arm peripheral artery disease, or known anatomic variants prohibiting TRA on both sides.
• • Patients with medical conditions that may cause non-compliance with the study protocol and/or may confound the data interpretation.
• • Patients unable to provide written informed consent.