Assessment for Implementation Methods in Sepsis

Launched by RHODE ISLAND HOSPITAL · Aug 4, 2022

Keywords

ClinConnect Summary

This clinical trial, called "Assessment for Implementation Methods in Sepsis," is looking at how different treatment approaches for sepsis (a serious infection) can help improve patient outcomes. Specifically, it compares two treatment plans: one that focuses on starting treatment within one hour of diagnosis and another that allows for treatment to start within three hours. The goal is to see which approach leads to better survival rates and fewer complications, like respiratory failure, for patients who come to the emergency department with sepsis. The trial will also analyze patient data to identify specific groups of patients that may respond better to certain treatments.

To participate in this trial, you must be an adult aged 18 or older and meet specific criteria indicating that you are experiencing sepsis within six hours of arriving at the emergency room. Certain patients, such as those who are pregnant, transferred from another hospital, or those receiving comfort care, are not eligible. If you choose to participate, you will receive one of the two treatment plans being studied, and your progress will be monitored closely to gather important information about the effectiveness of these approaches. This trial is currently recruiting participants, and your involvement could help shape future treatments for sepsis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults \>=18
• • Patient meets criteria for time zero (sepsis within 6 hours of ED triage and the 3 criteria-infection, 2 SIRS and 1 or more organ dysfunctions, must be met within 3 hours of each other.
• Exclusion Criteria:
• • Last admission for patients admitted to same hospital once
• • Pregnant women
• • All transfers from another hospital
• • Individuals who are made comfort care only within 6 hours of admission to ED
• • Moribund patients