Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Launched by UNIVERSITY OF MINNESOTA · Aug 5, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how to improve deep brain stimulation (DBS) for people with epilepsy who have not found relief from medications and are not able to have surgery. DBS is a treatment that uses a device implanted in the brain to help reduce seizures, but many patients still experience seizures even with this therapy. The researchers aim to optimize the settings of the stimulation to better meet each patient's individual needs, using specific measurements to guide these adjustments.

To be eligible for this study, participants need to have epilepsy that doesn't respond to medication and must already have a deep brain stimulator implanted. The trial is open to adults aged 65 to 74, regardless of gender. Participants will work with the research team to fine-tune their stimulation settings, which may lead to a better control of their seizures. It’s important to note that individuals with severe dementia may not be able to participate in this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • medically refractory epilepsy
• • already have a deep brain stimulator in place
• Exclusion Criteria:
• • severe dementia at investigator discretion