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Search / Trial NCT05493813

Total Intravenous Anesthesia Versus Sevoflurane Anesthesia for Endovascular Thrombectomy in Acute Ischemic Stroke

Launched by TAIPEI VETERANS GENERAL HOSPITAL, TAIWAN · Aug 7, 2022

Trial Information

Current as of September 09, 2025

Recruiting

Keywords

Ischemic Stroke General Anesthesia Total Intravenous Anesthesia Postoperative Delirium Postoperative Cognitive Dysfunction

ClinConnect Summary

This clinical trial is exploring the best type of anesthesia to use during a procedure called endovascular thrombectomy, which is performed on patients experiencing an acute ischemic stroke caused by a blocked blood vessel in the brain. The trial compares two different methods of general anesthesia: one using a gas called sevoflurane and the other using a medication called propofol delivered through an IV. Researchers want to see which method leads to fewer problems like confusion or memory issues after the procedure.

To participate in this trial, you need to be between 20 and 90 years old and diagnosed with a specific type of stroke that requires thrombectomy. You should also be willing to sign consent to join the study. If you choose to participate, the team will closely monitor your anesthesia and blood pressure during the procedure to ensure your safety and comfort. This study aims to find the best anesthesia approach for patients in similar situations, potentially improving recovery after strokes.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of acute ischemic stroke with large vessel occlusion who are scheduled to undergo endovascular thrombectomy procedure, and
  • Must be age of 20 to 90
  • Must fulfill the indications for endovascular thrombectomy in acute ischemic stroke according to the American Heart Association/American Stroke Association 2018 Guidelines for the early management of patients with acute ischemic stroke and 2019 Taiwan stroke society guideline for endovascular thrombectomy in acute ischemic stroke, and
  • Must agree to enroll into the clinical trial and sign the written informed consent from patients or delegates
  • Exclusion Criteria:
  • Allergy to allergy to the anesthetics used in this clinical study
  • Refusal for enrolling in study

About Taipei Veterans General Hospital, Taiwan

Taipei Veterans General Hospital, located in Taiwan, is a renowned medical institution dedicated to providing comprehensive healthcare and advancing medical research. As a prominent clinical trial sponsor, the hospital is committed to exploring innovative therapies and improving patient outcomes through rigorous scientific studies. With a multidisciplinary team of experienced researchers and clinicians, Taipei Veterans General Hospital prioritizes ethical standards and patient safety while contributing to the global medical community's knowledge base. Its state-of-the-art facilities and collaborative environment foster groundbreaking research that aims to address pressing healthcare challenges.

Locations

Taipei, Taiwan

Patients applied

0 patients applied

Trial Officials

Hsu Ma, MD, PhD

Study Chair

Institutional Review Board, Taipei Veterans General Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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