China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes

Launched by SECOND XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY · Aug 10, 2022

Keywords

ClinConnect Summary

The China Diabetes Type 1 Study (CD1S) is a national research project focused on understanding type 1 diabetes (T1D) in patients of all ages, especially young people diagnosed before the age of 20. The study is designed to gather information from patients who were hospitalized between January 1, 2016, and December 31, 2021, and will continue with new participants starting in 2022. This research aims to create a registry that helps track the experiences and treatment of individuals living with T1D.

To join the study, participants must have a confirmed diagnosis of type 1 diabetes or be children and adolescents diagnosed with diabetes before they turned 20, regardless of the type. Key criteria for eligibility include having started insulin therapy after their diabetes diagnosis and having certain medical conditions related to their diabetes. If you or someone you know meets these criteria, participating in the study could provide valuable insights into managing type 1 diabetes while contributing to important research efforts. Participants can expect to share their medical history and treatment experiences, helping to improve understanding and care for type 1 diabetes in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with type 1 diabetes mellitus of any duration; meeting criteria (1) or any of (2) or any of (3)
• • 1. Clinical diagnosis of type 1 diabetes by a specialist
• • 2. Age at onset \< 15 years; no overweight or obesity at onset; previous diabetic ketoacidosis; highest random C-peptide \< 200 pmol/L
• • 3. Initiation and continuation of insulin therapy (except pancreatic or islet transplantation) after diagnosis; positive islet autoantibodies Or 2. Children and adolescents with diabetes mellitus at age of onset \<= 20 years, regardless of type and duration of disease.
• Exclusion Criteria:
• • For enrolment of patients with T1D, exclusion was made if any of the following criteria were met (not applicable to those with onset under 20 years of age)
• • No insulin dependence for at least 6 months after diagnosis of diabetes mellitus.
• • No DKA for 1 month off insulin for those with a history of diabetes \> 1 year. ③ C-peptide \> 800 pmol/L at any time point.