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Search / Trial NCT05506553

Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision

Launched by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST · Aug 16, 2022

Trial Information

Current as of August 25, 2025

Unknown status

Keywords

Cataract Presbyopia Astigmatism

ClinConnect Summary

Cataract is a condition caused by progressive clouding of the natural crystalline lens inside the eye. This leads to impairment of visual performance. This condition represents a huge disease burden and is a leading cause of reversible blindness worldwide. In the UK and the developed world, the incidence of cataract induced blindness continues to increase, secondary to an aging population and increasingly common risk factors such as diabetes. In 1950, Harold Ridley inserted an intraocular lens following cataract extraction at St Thomas' Hospital. This was the first recorded surgery of its k...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Bilateral cataract requiring surgical intervention,
  • age over 18 years
  • able to understand informed consent and the objectives of the trial,
  • not pregnant, not breast feeding
  • no previous intraocular eye surgery
  • good visual potential in both eyes
  • corneal astigmatism of 1.5 to 6 dioptres
  • Exclusion Criteria:
  • * Any patient with other ocular condition that might reduce visual acuity and hence confound the results such as:
  • visually impairing age-related macular degeneration
  • Advanced glaucoma
  • previous retinal vascular disorders
  • previous retinal detachment or tear
  • any visually impairing neuro-ophthalmological condition
  • any inherited retinal disorder or pathology
  • previous strabismus surgery or record of amblyopia
  • previous visually impairing CVA, TIA or other vaso-occlusive disease
  • already enrolled in another study or trial
  • instability of keratometry or biometry measurements
  • irregular astigmatism
  • previous significant trauma to eye

About Guy's And St Thomas' Nhs Foundation Trust

Guy's and St Thomas' NHS Foundation Trust is a leading healthcare organization in the United Kingdom, renowned for its commitment to delivering high-quality patient care, innovative research, and clinical excellence. As a prominent academic health science center, the Trust integrates cutting-edge research with clinical practice, facilitating the translation of scientific discoveries into improved treatment options. With a diverse portfolio of clinical trials across various medical specialties, Guy's and St Thomas' NHS Foundation Trust plays a pivotal role in advancing healthcare knowledge and enhancing patient outcomes, while maintaining the highest ethical standards in research and patient safety.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

David O'Brart, MBBS, MD

Study Director

Guy's and St Thomas' NHS Foundation Trust

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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