Efficacy and Safety of Astragalus for Non-motor Symptoms of α-Synucleinopathy
Launched by FUJIAN MEDICAL UNIVERSITY UNION HOSPITAL · Aug 16, 2022
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a natural supplement called astragalus on non-motor symptoms in people with certain nervous system disorders, including Parkinson's disease (PD), Multiple System Atrophy (MSA), and Dementia with Lewy Bodies (DLB). These disorders can cause not only movement problems but also issues like low blood pressure when standing up, which can lead to dizziness and falls. The trial aims to see if astragalus can help manage these troubling symptoms safely.
To participate in the study, individuals must be adults diagnosed with PD, MSA, or DLB and have low blood pressure when standing, along with some cognitive difficulties. Unfortunately, those with allergies to astragalus, other specific medical conditions, or who are pregnant or breastfeeding are not eligible. If you join the trial, you'll be monitored before and after taking astragalus to see how it affects your symptoms. This study is currently looking for participants, so if you think you might qualify, it could be a great opportunity to contribute to research that aims to improve quality of life for people with these conditions.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Participants with a clinical diagnosis of PD, MSA and DLB, with orthostatic hypotension.
- • Participants with cognitive disorder.
- • Adults signed informed consents.
- Exclusion Criteria:
- • Patients with history of astragalus allergy.
- • Patients with secondary Parkinsonism that cannot be excluded.
- • Patients with diseases that may cause other types of hypotension or similar symptoms/signs because of hypotension
- • Patients with other medical conditions requiring treatments that may affect blood pressure.
- • Patients with other neurological disorders.
- • Patients with serious comorbidities and immune diseases.
- • Uncooperative patients.
- • Pregnant or lactating women.
About Fujian Medical University Union Hospital
Fujian Medical University Union Hospital is a leading medical institution in China, dedicated to advancing healthcare through innovative clinical research and comprehensive patient care. As a prominent clinical trial sponsor, the hospital is committed to conducting high-quality studies that contribute to the development of new therapies and medical interventions. With a multidisciplinary team of experienced healthcare professionals and researchers, Fujian Medical University Union Hospital emphasizes ethical standards, patient safety, and scientific rigor in all its clinical trials, fostering collaboration with both local and international research partners to enhance medical knowledge and improve patient outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Fuzhou, Fujian, China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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