Tight Control of Gouty Arthritis Compared to Usual Care

Launched by UNIVERSITY OF EDINBURGH · Aug 18, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new way to manage gout, a painful condition caused by the buildup of urate crystals in the joints. The researchers want to see if a self-management approach, where patients can monitor their urate levels at home using a simple finger prick test and a smartphone app called GoutSMART, can reduce the number of gout flares better than standard care. In the past, many patients haven't received effective treatment, and this trial aims to find out if actively adjusting medication based on personal urate levels leads to better control of the condition over two years.

To participate in the trial, you need to be at least 18 years old and have experienced at least one gout flare in the past year. You'll also need a smartphone to use the GoutSMART app. During the trial, you'll be randomly assigned to either use the self-management approach or continue with usual care. It's important to know that some people may not be eligible if they're already on maximum medication for gout or have certain health conditions. Overall, this trial hopes to provide better options for managing gout and improving patients’ quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Provision of informed consent.
• • Age ≥18 years.
• • Patient has sustained at least one flare of gout in the previous 12 months.
• • Confirmed clinical diagnosis of gout as per ACR/EULAR criteria
• • Serum urate \>0.36mm/L.
• • Patient has a smart phone and is able to install GoutSMART application.
• Exclusion Criteria:
• • Subject unable to provide consent
• • Patient on maximum urate lowering therapy or where therapy cannot be escalated further due to intolerance/adverse reaction to either allopurinol or febuxostat.
• • End stage renal failure/transplant
• • Current prescription of medication known to interact with xanthine oxidase inhibitors such as azathioprine or mercapto-purine.