Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment

Launched by AIR FORCE MILITARY MEDICAL UNIVERSITY, CHINA · Aug 21, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a condition called functional dyspepsia (FD), which is a common digestive issue causing symptoms like stomach pain, bloating, and discomfort. The researchers want to learn more about how patients respond to different medications and why some people continue to experience symptoms even after treatment. They are particularly interested in understanding how psychological factors, like anxiety and sleep problems, may affect recovery.

To participate in this trial, you need to be at least 18 years old and meet specific criteria, including having had a normal stomach examination and ultrasound in the past year. Unfortunately, some individuals will not be eligible, such as those with certain serious health conditions or who are currently pregnant. If you join the study, you can expect to receive medication and be monitored to see how well it works for you. This trial aims to provide better insights into treating functional dyspepsia and improving patient outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. age ≥18 years old
• • 2. Patients who met Rome IV criteria
• • 3. Normal upper endoscopy and abdominal ultrasonography within one year
• Exclusion Criteria:
• 1. Patients with local or systemic diseases which may cause dyspeptic symptoms:
• • Known active peptic ulcer, cholecystitis, gallstone, gastrointestinal obstruction, gastroparesis, and etc.; Known acute or chronic injury of liver or kidney; Obvious hematological abnormality, or endocrine and metabolic diseases; Known malignancy; Obvious cardiovascular or cerebrovascular diseases (such as coronary heart disease, arrhythmia, cerebral infarction and etc.; Other conditions which may be associated with dyspeptic symptoms (such as NSAIDs associated dyspepsia)
• • 2. organ failure defined by Marshall standard
• • 3. severe psychiatric illnesses
• • 4. known malignancy
• • 5. pregnancy or lactation
• • 6. unable to provide consent
• • 7. suspected or identified bowel obstruction