Overcoming Nicotine Dependence to Enable Quitting

Launched by RUSH UNIVERSITY MEDICAL CENTER · Aug 23, 2022

Keywords

ClinConnect Summary

This clinical trial, titled "Overcoming Nicotine Dependence to Enable Quitting," is exploring new approaches to help smokers who aren't ready to quit just yet. The study focuses on a concept called "practice quitting," which involves trying to go without smoking for a few hours or days without the pressure of committing to stop for good. Researchers want to see if this practice can encourage more permanent quitting down the line. They will compare two different types of counseling—one that encourages practice quitting and another called Motivational Interviewing—and provide some participants with a four-week supply of nicotine replacement therapy (like lozenges and patches) to see how these strategies work.

To participate, individuals need to be at least 18 years old, smoke at least five cigarettes a day, and not be planning to quit within the next month. They should also be motivated to either quit or reduce their smoking within the next six months. Participants will need to be comfortable using a smartphone for study activities and must be residents of the continental United States. This trial aims to offer new insights into helping smokers take their first steps towards quitting, even if they aren't ready to stop completely right now.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Eligible participants will be males and females who:
• • 1. are 18 years or older
• • 2. report current daily cigarette smoking (≥ 5 cigarettes per day)
• • 3. are not planning to quit in the next 30 days
• • 4. are not currently engaged in smoking cessation treatment
• • 5. are motivated to quit or engage in a non-cessation goal (i.e., reduce smoking, learn more about treatment options, and/ or try out skills to change smoking) in the next 6 months
• • 6. are English speaking
• • 7. reside in the continental United States
• • 8. have access to a smartphone that can be used to complete study procedures
• Exclusion Criteria:
• Participants will be excluded for daily vaping/ electronic cigarettes use (i.e., use for ≥ 25 days within past 30 days) and any FDA contraindications for NRT use if they:
• • 1. are pregnant/breastfeeding
• • 2. had recent cardiovascular trauma such as myocardial infarction
• • 3. had a stroke within the past 3 months