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Search / Trial NCT05513911

Intermittent Hypoxia and Upper Extremity EMG Recordings in Individuals With Spinal Cord Injury

Launched by SHIRLEY RYAN ABILITYLAB · Aug 22, 2022

Trial Information

Current as of July 09, 2025

Completed

Keywords

Acute Intermittent Hypoxia Motor Unit Upper Extremity

ClinConnect Summary

It has been shown previously that there is an increase in strength in survivors of spinal cord injury after brief bouts of Acute Intermittent Hypoxia. In this study, participants are fitted with a high density EMG electrode on the biceps brachii, and attached to a load cell at the wrist, they are asked to flex and extend their elbow at various levels of intensity. This is performed before and after the 30 minute session of AIH. The investigators hope to identify specific types of motor units of the upper extremity of survivors of spinal cord injury after AIH to help further our understandin...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • History of Spinal Cord Injury from C3-T4
  • Non-progressive spinal cord injury
  • More than 6 months since initial Spinal Cord injury
  • Ability to understand and willingness to sign written informed consent
  • Exclusion Criteria:
  • Presence of any of the following medical conditions: Congestive heart failure, arrhythmia, uncontrolled high blood pressure, uncontrolled diabetes mellitus, COPD/emphysema and severe asthma
  • Persons with known coronary artery disease, a history of myocardial infarction, or known carotid or intracerebral artery stenosis
  • Medical clearance will be required if participant is taking any other investigational agents
  • Women who are pregnant or nursing
  • Individuals with tracheostomy
  • Cannot pursue other research studies which may interfere
  • Unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Prisoners

About Shirley Ryan Abilitylab

Shirley Ryan AbilityLab is a leading research and rehabilitation institute dedicated to advancing the science of physical medicine and rehabilitation. Based in Chicago, Illinois, the organization integrates clinical care, research, and education to enhance the quality of life for individuals with disabilities and chronic conditions. Known for its innovative approach, Shirley Ryan AbilityLab conducts clinical trials that aim to develop and evaluate cutting-edge therapies and technologies, fostering a collaborative environment that bridges the gap between laboratory research and patient care. Through its commitment to excellence, the institute strives to empower patients and improve outcomes in rehabilitation medicine.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

William Z Rymer, MD, PhD

Principal Investigator

Shirley Ryan AbilityLab

Milap Sandhu, PhD

Principal Investigator

Shirley Ryan AbilityLab

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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