A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
Launched by ELI LILLY AND COMPANY · Aug 23, 2022
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new treatment called imlunestrant to see how well it works compared to standard hormone therapy for patients with early breast cancer. The patients being considered for this study have breast cancer that is estrogen receptor positive (ER+) and human epidermal growth factor receptor 2 negative (HER2-). They also need to have already undergone hormone therapy for 2 to 5 years and have a higher risk of their cancer coming back. The entire study could last up to 10 years, and they are currently looking for participants.
To be eligible for this trial, participants must have early-stage breast cancer that has been surgically removed and should have received at least 2 years of hormone therapy. They cannot have any signs of cancer spreading to other parts of the body or a history of other cancers, except for certain very specific cases. Participants will be monitored closely throughout the study and will have regular check-ups. This trial is open to everyone aged 65 to 74, regardless of gender, and aims to find better treatment options for patients at risk of breast cancer recurrence.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Have a diagnosis of ER+, HER2- early-stage, resected, invasive breast cancer without evidence of distant metastasis.
- • Participants must have received at least 24 months but not more than 60 months of any adjuvant ET, from time of adjuvant ET initiation.
- • Participants may have received (neo) adjuvant chemotherapy and/or targeted therapy with a CDK4/6- or PARP- inhibitor.
- • Must have an increased risk of disease recurrence based on clinical-pathological risk features.
- • Have a Performance Status of 0 or 1 on the Eastern Cooperative Oncology Group scale.
- • Have adequate organ function.
- Exclusion Criteria:
- • Have any evidence of metastatic disease (including contralateral ALN) or inflammatory breast cancer at primary breast cancer diagnosis.
- • Participants with more than a 6-month consecutive gap in therapy during the course of prior adjuvant ET.
- • Participants who have completed or discontinued prior adjuvant ET \>6 months prior to screening.
- • Participants with a history of previous breast cancer are excluded, with the exception of ipsilateral DCIS treated by locoregional therapy alone ≥5 years ago.
- • Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through 180 days after the last dose of study intervention.
- • Participant has previously received ET of any duration for breast cancer prevention (tamoxifen or AIs) or raloxifene.
- • Participants with a history of any other cancer.
- • Have serious preexisting medical conditions that, in the judgment of the investigator, would preclude participation in this study.
About Eli Lilly And Company
Eli Lilly and Company is a global healthcare leader dedicated to creating innovative medicines that improve patient outcomes across a range of therapeutic areas, including diabetes, oncology, immunology, and neurodegenerative diseases. With a rich history of scientific research and a commitment to advancing healthcare, Lilly invests significantly in clinical trials to develop new treatments and enhance existing therapies. The company prioritizes patient safety and ethical standards in its clinical research, fostering collaboration with healthcare professionals and stakeholders to ensure the delivery of high-quality, evidence-based solutions that address unmet medical needs worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Boston, Massachusetts, United States
New York, New York, United States
Saint Louis, Missouri, United States
Abington, Pennsylvania, United States
Providence, Rhode Island, United States
Brussels, , Belgium
Chicago, Illinois, United States
Toronto, Ontario, Canada
Fort Sam Houston, Texas, United States
Staten Island, New York, United States
New Orleans, Louisiana, United States
Chicago, Illinois, United States
New York, New York, United States
Liverpool, New South Wales, Australia
Lebanon, New Hampshire, United States
Madrid, , Spain
Chicago, Illinois, United States
Montreal, Quebec, Canada
Madrid, , Spain
Lewiston, Maine, United States
Nashville, Tennessee, United States
Hobart, Tasmania, Australia
Box Hill, Victoria, Australia
Boston, Massachusetts, United States
Washington, District Of Columbia, United States
Baltimore, Maryland, United States
Rochester, New York, United States
Philadelphia, Pennsylvania, United States
Seoul, , Korea, Republic Of
Worcester, Massachusetts, United States
New Brunswick, New Jersey, United States
Jacksonville, Florida, United States
Sapporo, Hokkaido, Japan
Launceston, Tasmania, Australia
Honolulu, Hawaii, United States
Washington, District Of Columbia, United States
Portland, Oregon, United States
Syracuse, New York, United States
Omaha, Nebraska, United States
Saint Louis, Missouri, United States
Boise, Idaho, United States
Fort Lauderdale, Florida, United States
Stuttgart, , Germany
Lebanon, New Hampshire, United States
Charlottesville, Virginia, United States
Stevenage, Hertfordshire, United Kingdom
Tampa, Florida, United States
Knoxville, Tennessee, United States
Peoria, Illinois, United States
Hackensack, New Jersey, United States
Fort Worth, Texas, United States
Madrid, , Spain
Calgary, Alberta, Canada
La Jolla, California, United States
Hollywood, Florida, United States
Kyoto, , Japan
Taipei, , Taiwan
Atlanta, Georgia, United States
Huntsville, Alabama, United States
Danvers, Massachusetts, United States
Coffs Harbour, New South Wales, Australia
The Woodlands, Texas, United States
Austin, Texas, United States
York, Maine, United States
London, , United Kingdom
Montreal, Quebec, Canada
Woodville, South Australia, Australia
Milford, Massachusetts, United States
Atlanta, Georgia, United States
Honolulu, Hawaii, United States
Gosford, New South Wales, Australia
Alicante, , Spain
Charlottesville, Virginia, United States
Cincinnati, Ohio, United States
Eugene, Oregon, United States
Orange, California, United States
Hiroshima, , Japan
Tokyo, , Japan
Madrid, , Spain
Geelong, Victoria, Australia
Mumbai, Maharashtra, India
Barcelona, , Spain
Madrid, , Spain
La Laguna, Santa Cruz De Tenerife, Spain
Madrid, , Spain
Valladolid, , Spain
Lleida, , Spain
Santa Cruz De Tenerife, , Spain
Colchester, Essex, United Kingdom
Ota, Gunma, Japan
Sapporo, Hokkaido, Japan
Nishinomiya, Hyogo, Japan
Utsunomiya, Tochigi, Japan
Okayama, , Japan
Mount Kisco, New York, United States
Seoul, , Korea, Republic Of
Taipei, , Taiwan
Paris, , France
Melbourne, Victoria, Australia
Bethesda, Maryland, United States
London, Ontario, Canada
Darlinghurst, New South Wales, Australia
Canton, Ohio, United States
Nagoya, Aichi, Japan
Kanazawa, Ishikawa, Japan
Sevilla, , Spain
New Haven, Connecticut, United States
Tainan, , Taiwan
Sevilla, , Spain
Aurora, Colorado, United States
Kaohsiung, , Taiwan
Seoul, , Korea, Republic Of
Augusta, Georgia, United States
Fukuyama, Hiroshima, Japan
Paris, , France
Abington, Pennsylvania, United States
Paris, , France
Erlangen, Bayern, Germany
Albuquerque, New Mexico, United States
Merced, California, United States
Columbus, Ohio, United States
Patras, , Greece
Perpignan, , France
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Taipei, , Taiwan
Brno, , Czechia
Bratislava, , Slovakia
Prague, , Czechia
Yokohama, Kanagawa, Japan
Niigata Shi, Niigata, Japan
Chuo Ku, Tokyo, Japan
Tokushima, , Japan
Nanjing, Jiangsu, China
Magdeburg, Sachsen Anhalt, Germany
Jaen, , Spain
Paris, , France
Seoul, , Korea, Republic Of
Bunkyo Ku, Tokyo, Japan
Barcelona, , Spain
Bayonne, , France
Fairfax, Virginia, United States
Manchester, , United Kingdom
Tyler, Texas, United States
Beijing, Beijing, China
Guangzhou, , China
San Francisco, California, United States
San Juan, , Argentina
Tsukuba, Ibaraki, Japan
Chiba, , Japan
Barcelona, , Spain
Brooklyn, New York, United States
Zaragoza, , Spain
Valencia, , Spain
Hiroshima, , Japan
Changsha, Hunan, China
Nanjing, Jiangsu, China
Yokohama, , Japan
Reading, , United Kingdom
Melbourne, Victoria, Australia
Ottignies, , Belgium
Shepparton, Victoria, Australia
Seoul, , Korea, Republic Of
Larissa, , Greece
Brussels, , Belgium
Townsville, Queensland, Australia
Santo André, São Paulo, Brazil
Changchun, Jilin, China
New Brunswick, New Jersey, United States
Lyon, , France
Nagoya, Aichi, Japan
Fukushima, , Japan
Logroño, La Rioja, Spain
Matsuyama, Ehime, Japan
Bratislava, , Slovakia
Taoyuan, , Taiwan
Berlin, , Germany
Hiroshima, , Japan
Graz, Steiermark, Austria
Potsdam, Brandenburg, Germany
Ulm, , Germany
Freiburg Im Breisgau, , Germany
Brest, , France
Porto Alegre, Rio Grande Do Sul, Brazil
Columbia, Missouri, United States
Liège, , Belgium
Hradec Kralove, , Czechia
Westbury, New York, United States
Dallas, Texas, United States
Goyang Si, , Korea, Republic Of
Oaxaca, , Mexico
Wuhan, Hubei, China
Shenzhen, Guangdong, China
Wuhan, Hubei, China
Saint Louis, Missouri, United States
Mackay, Queensland, Australia
Fukuoka, , Japan
Kyoto, , Japan
Hangzhou, Zhejiang, China
Changsha, Hunan, China
Baton Rouge, Louisiana, United States
Athens, , Greece
Mcallen, Texas, United States
Taipei, , Taiwan
Ieper, , Belgium
Reus, , Spain
Nanchang, Jiangxi, China
Créteil, , France
Salvador, Bahia, Brazil
Milano, , Italy
Beijing, Beijing, China
Ostrava, , Czechia
Mannheim, , Germany
Seongnam, , Korea, Republic Of
Seoul, , Korea, Republic Of
Leuven, Vlaams Brabant, Belgium
Southport, Queensland, Australia
Shanghai, Shanghai, China
Wien, , Austria
Incheon, , Korea, Republic Of
Fort Belvoir, Virginia, United States
Seoul, , Korea, Republic Of
Shanghai, , China
Charleroi, Hainaut, Belgium
Madrid, , Spain
Willow Grove, Pennsylvania, United States
Nashville, Tennessee, United States
Sagamihara, Kanagawa, Japan
Plymouth, Devon, United Kingdom
Santo André, , Brazil
Barcelona, , Spain
Pau, , France
Taipei City, Taipei, Taiwan
Manchester, Greater Manchester, United Kingdom
Shenzhen, Guangdong, China
Las Cruces, New Mexico, United States
Suhl, , Germany
Shantou, Guangdong, China
Haikou, Hainan, China
Reus, Tarragona, Spain
Sapporo, , Japan
Suzhou, Jiangsu, China
Gilbert, Arizona, United States
Burgos, , Spain
Seoul, , Korea, Republic Of
Phoenix, Arizona, United States
Barcelona, , Spain
Bethlehem, Pennsylvania, United States
Fuzhou, Fujian, China
Springdale, Arkansas, United States
Paris, , France
Anderlecht, , Belgium
Stockton, California, United States
Granada, , Spain
Parma, , Italy
Dallas, Texas, United States
Toronto, Ontario, Canada
Madrid, , Spain
Changchun, Jilin, China
Gera, , Germany
Beijing, Beijing, China
Tijuana, Baja California, Mexico
Savannah, Georgia, United States
Debrecen, , Hungary
Hangzhou, Zhejiang, China
Wuhan, Hubei, China
Monterey, California, United States
Padova, , Italy
Badajoz, , Spain
Luoyang, Henan, China
Heraklion, , Greece
Budapest, , Hungary
Kocaeli, , Turkey
Berlin, , Germany
Yokohama, Kanagawa, Japan
Tucson, Arizona, United States
Dongguan, Guangdong, China
Beijing, Beijing, China
Lugo, , Spain
Budapest, , Hungary
Hangzhou, Zhejiang, China
Sendai Shi, Miyagi, Japan
Daegu, , Korea, Republic Of
Cheongju Si, , Korea, Republic Of
Matsumoto, Nagano, Japan
Homburg, Saarland, Germany
Brussels, , Belgium
Columbus, Ohio, United States
Mar Del Plata, Buenos Aires, Argentina
Bengbu, Anhui, China
Ningbo, Zhejiang, China
Haifa, ḥeifā, Israel
Kumamoto, , Japan
Guadalajara, Jalisco, Mexico
Edirne, , Turkey
Quebec City, Quebec, Canada
Tel Aviv, , Israel
Speyer, Rheinland Pfalz, Germany
Fort Worth, Texas, United States
Shijiazhuang, Hebei, China
Midlothian, Virginia, United States
Beijing, Beijing, China
Chandigarh, , India
Ulsan, , Korea, Republic Of
Taipei, , Taiwan
Hershey, Pennsylvania, United States
Shizuoka, , Japan
Tainan, , Taiwan
Clayton, Victoria, Australia
Lincoln, Nebraska, United States
Wuhan, Hubei, China
Youngstown, Ohio, United States
Jyväskylä, , Finland
Gifu, , Japan
Fairhaven, Massachusetts, United States
Bergamo, , Italy
Yueyang, Hunan, China
Chiba Shi, Chiba, Japan
Gaziantep, , Turkey
Hasselt, Limburg, Belgium
Subiaco, Western Australia, Australia
Nice, , France
Hirakata, Osaka, Japan
Thessaloniki, , Greece
Besançon, Doubs, France
Saint Grégoire, , France
Istanbul, , Turkey
New York, New York, United States
Toledo, Ohio, United States
Jerusalem, Yerushalayim, Israel
Kawasaki, Kanagawa, Japan
Chandigarh, , India
Camden, New Jersey, United States
Yokohama, Kanagawa, Japan
Kagoshima, , Japan
Yantai, Shandong, China
Tiwi, Northern Territory, Australia
Kamogawa, Chiba, Japan
Guangzhou, Guangdong, China
Jinan, Shandong, China
Xiangyang, Hubei, China
Brno, Brno Město, Czechia
Porto Alegre, Rio Grande Do Sul, Brazil
Edirne, , Turkey
Beijing, Beijing, China
Ioannina, , Greece
Salzburg, , Austria
Brindisi, , Italy
Ieper, West Vlaanderen, Belgium
Xi'an, , China
Adana, , Turkey
Sakarya, , Turkey
Bakersfield, California, United States
Thessaloniki, , Greece
Changhua, , Taiwan
Toronto, Ontario, Canada
Ijui, Rio Grande Do Sul, Brazil
Shinjyuku Ku, Tokyo, Japan
Mannheim, Baden Württemberg, Germany
Frankfurt, Hessen, Germany
Edinburgh, Midlothian, United Kingdom
Terni, , Italy
Fremont, California, United States
Singapore, Central Singapore, Singapore
Hyderabad, Telangana, India
La Tronche, , France
Toledo, , Spain
Maastricht, Limburg, Netherlands
Zaandam, Noord Holland, Netherlands
Valenciennes, , France
Jonesboro, Arkansas, United States
Seongnam Si, , Korea, Republic Of
Deventer, Overijssel, Netherlands
Tübingen, , Germany
Greeley, Colorado, United States
San Antonio, Texas, United States
Dortmund, Nordrhein Westfalen, Germany
Brasilia, Distrito Federal, Brazil
Huizhou, Guangdong, China
Zhengzhou, Henan, China
Kecskemét, , Hungary
Jaen, Jaén, Spain
Miami, Florida, United States
Koto, Tokyo, Japan
Seongnam, Kyǒnggi Do, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Barcelona, Barcelona [Barcelona], Spain
Rochester, New York, United States
Firenze, Toscana, Italy
Paris, , France
Hammond, Louisiana, United States
Los Alamitos, California, United States
Denton, Texas, United States
Flower Mound, Texas, United States
San Francisco, California, United States
Rozzano, Milano, Italy
Rochester, Minnesota, United States
Miyazaki, , Japan
Bhubaneswar, Odisha, India
Changde, Hunan, China
Mobile, Alabama, United States
East Brunswick, New Jersey, United States
Huntsville, Alabama, United States
Roanoke, Virginia, United States
Temple, Texas, United States
Lisboa, , Portugal
Dallas, Texas, United States
Sao Paulo, , Brazil
Haifa, , Israel
Montréal, Quebec, Canada
Ankara, , Turkey
La Roche Sur Yon, , France
San Francisco, California, United States
Chihuahua, , Mexico
Izmir, , Turkey
Dublin, , Ireland
Takasaki, Gunma, Japan
Gyeongsan Si, Kyǒngsangbuk Do, Korea, Republic Of
Mersin, , Turkey
Baoding, , China
Beijing, Beijing, China
Pau, Pyrénées Atlantiques, France
Kortrijk, West Vlaanderen, Belgium
Caba, Ciudad Autónoma De Buenos Aire, Argentina
Kecskemét, Bács Kiskun, Hungary
Izumo, Shimane, Japan
Shinagawa, Tokyo, Japan
Kyoto, , Japan
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Ulsan, Ulsan Kwangyǒkshi, Korea, Republic Of
Colorado Springs, Colorado, United States
Howell, New Jersey, United States
San Pedro Garza Garcia, , Mexico
Bayonne, Pyrénées Atlantiques, France
Craiova, Dolj, Romania
Otopeni, Ilfov, Romania
Goyang Si, Kyǒnggi Do, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Mendoza, , Argentina
Sydney, New South Wales, Australia
Incheon, , Korea, Republic Of
Sant Cugat Del Vallès, Barcelona [Barcelona], Spain
Madrid, Madrid, Comunidad De, Spain
Ankara, , Turkey
São Paulo, , Brazil
Covington, Louisiana, United States
Antalya, , Turkey
Assen, Drenthe, Netherlands
Heraklion, Irakleío, Greece
Brasov, Brașov, Romania
Bordeaux, Aquitaine, France
Singapore, Central Singapore, Singapore
Corbeil Essonnes, île De France, France
Chaidari, , Greece
Kfar Saba, Hamerkaz, Israel
Chengdu, Sichuan, China
Prague, Praha 4, Czechia
Bursa, , Turkey
Malatya, , Turkey
Chongqing, Chongqing, China
Nashik, Maharashtra, India
Ciudad Madero, Tamaulipas, Mexico
Nyiregyhaza, Szabolcs Szatmár Bereg, Hungary
Springfield, Illinois, United States
Anyang, Henan, China
Brest, Bretagne, France
Asheville, North Carolina, United States
Corvallis, Oregon, United States
Dalian, Liaoning, China
Shaoxing, Zhejiang, China
Taipei City, Taipei, Taiwan
Candiolo, Torino, Italy
Sleepy Hollow, New York, United States
Melbourne, Victoria, Australia
Nedlands, Western Australia, Australia
Berazategui, Buenos Aires, Argentina
Viedma, Río Negro, Argentina
Namur, , Belgium
Londrina, Paraná, Brazil
Thessaloniki, Thessaloníki, Greece
Napoli, Campania, Italy
Changhua County, Changhua, Taiwan
Ankara, , Turkey
Mexico City, Distrito Federal, Mexico
Providence, Rhode Island, United States
Huai'an, Jiangsu, China
Chaidari, Attikí, Greece
Larissa, Thessalía, Greece
Hong Kong, , Hong Kong
Denison, Texas, United States
São Paulo, , Brazil
Jiangmen, Guangdong, China
Gera, Thüringen, Germany
Jaipur, Rajasthan, India
Ottignies, Brabant Wallon, Belgium
Preston, England, United Kingdom
Palma, , Spain
Ballarat Central, Victoria, Australia
Freiburg Im Breisgau, Baden Württemberg, Germany
Malaga, Málaga, Spain
Stuttgart, Baden Württemberg, Germany
Saitama, , Japan
São Paulo, , Brazil
Vienna, Wien, Austria
Suhl, Thüringen, Germany
San Miguel De Tucumán, Tucumán, Argentina
Brussels, Bruxelles Capitale, Région De, Belgium
Liège, , Belgium
Barretos, São Paulo, Brazil
São José Do Rio Preto, São Paulo, Brazil
Fuzhou, Fujian, China
Hradec Kralove, Hradec Králové, Czechia
Prague, Praha 4, Czechia
Tampere, Pirkanmaa, Finland
Kawasaki, Kanagawa, Japan
Osaka, , Japan
Oaxaca, , Mexico
New Taipei City, , Taiwan
Greenville, South Carolina, United States
Yahaba Cho, Shiwa Gun, Iwate, Japan
Madrid, , Spain
San Nicolas, Buenos Aires, Argentina
Vitória, Espírito Santo, Brazil
A Coruña, , Spain
Buenos Aires, Ciudad Autónoma De Buenos Aire, Argentina
Eugene, Oregon, United States
Sint Niklaas, Oost Vlaanderen, Belgium
Gdynia, Pomorskie, Poland
Brest, Finistère, France
Thiruvananthapuram, Kerala, India
Vaasa, Pohjanmaa, Finland
Vandoeuvre Lès Nancy, Lorraine, France
Essen, Nordrhein Westfalen, Germany
Thessaloniki, Kentrikí Makedonía, Greece
Macerata, , Italy
Ota, Gunma, Japan
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Brasov, , Romania
Northwood, Hertfordshire, United Kingdom
Torun, Kujawsko Pomorskie, Poland
Patras, Achaḯa, Greece
Athens, Attikí, Greece
Tainan City, Tainan, Taiwan
Adana, , Turkey
Mersin, , Turkey
Monterrey, Nuevo León, Mexico
Ningbo, Zhejiang, China
Río Cuarto, Córdoba, Argentina
Jerusalem, Yerushalayim, Israel
Oaxaca De Juarez, Oaxaca, Mexico
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Suwon Si, , Korea, Republic Of
Taichung, , Taiwan
New Orleans, Louisiana, United States
Flushing, New York, United States
Ramat Gan, Hamerkaz, Israel
Minneapolis, Minnesota, United States
Loveland, Colorado, United States
San Juan, , Argentina
Schwaz, Tirol, Austria
São Paulo, , Brazil
São Paulo, , Brazil
Changsha, Hunan, China
Urumqi, Xinjiang, China
Ningbo, Zhejiang, China
Prague, Praha 8, Czechia
Montpellier, Languedoc Roussillon, France
Saint Cloud, île De France, France
Kiel, Schleswig Holstein, Germany
Thessaloniki, Thessaloníki, Greece
Naples, Campania, Italy
Modena, , Italy
Cheonan Si, Chungcheongnam Do [Chungnam], Korea, Republic Of
Namdong Gu, , Korea, Republic Of
Suwon Si, Kyǒnggi Do, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
San Pedro Garza Garcia, Nuevo León, Mexico
Puebla, , Mexico
Den Haag, Zuid Holland, Netherlands
Barcelona, Barcelona [Barcelona], Spain
Barcelona, Catalunya [Cataluña], Spain
Ankara, , Turkey
Diyarbakir, , Turkey
Istanbul, , Turkey
Erlangen, Bayern, Germany
New York, New York, United States
Neijiang, Sichuan, China
Oulu, Pohjois Pohjanmaa, Finland
Helsinki, , Finland
Poitiers, Vienne, France
Athens, Attikí, Greece
Genova, Liguria, Italy
Shiwa Gun Yahaba Cho, Iwate, Japan
Hwasun Gun, Jeonranamdo, Korea, Republic Of
Seoul, Seoul Teukbyeolsi [Seoul], Korea, Republic Of
Mar Del Plata, Buenos Aires, Argentina
Monterrey, Nuevo León, Mexico
Ancona, , Italy
Pamplona, Navarra, Spain
Brooklyn, New York, United States
Los Angeles, California, United States
Torrance, California, United States
Hollywood, Florida, United States
Caba, Ciudad Autónoma De Buenos Aire, Argentina
Buenos Aires, , Argentina
San Juan, , Argentina
Pardubice, Pardubický Kraj, Czechia
Brest, Bretagne, France
La Roche Sur Yon, Vendée, France
Be'er Sheva, Hadarom, Israel
Petah Tikva, Hamerkaz, Israel
Tel Aviv, Tell Abīb, Israel
Misterbianco, Catania, Italy
Daegu, Taegu Kwangyǒkshi, Korea, Republic Of
Monterrey, Nuevo León, Mexico
San Luis Potosi, San Luis Potosí, Mexico
A Coruña, A Coruña [La Coruña], Spain
Palma, Balears [Baleares], Spain
Barcelona, Barcelona [Barcelona], Spain
Barcelona, Catalunya [Cataluña], Spain
Madrid, Madrid, Comunidad De, Spain
El Palmar, Murcia, Murcia, Región De, Spain
Reus, Tarragona [Tarragona], Spain
Izmir, Karsiyaka, İzmir, Turkey
Ankara, , Turkey
London, London, City Of, United Kingdom
Madrid, Madrid, Comunidad De, Spain
Buenos Aires, Ciudad Autónoma De Buenos Aire, Argentina
Capital, Córdoba, Argentina
Taichung City, Taichung, Taiwan
Fort Collins, Colorado, United States
Mineola, New York, United States
Burlington, Vermont, United States
Buenos Aires, , Argentina
Buenos Aires, , Argentina
Fortaleza, Ceará, Brazil
Curitiba, Paraná, Brazil
São Paulo, , Brazil
Horovice, Beroun, Czechia
La Chaussée Saint Victor, Centre, France
Saint Herblain, Loire Atlantique, France
Le Mans, Pays De La Loire, France
Zerifin, Hamerkaz, Israel
Warszawa, Mazowieckie, Poland
Opole, Opolskie, Poland
Lodz, łódzkie, Poland
Constanta, Constanța, Romania
București, , Romania
București, , Romania
Stanbul, İstanbul, Turkey
Helsinki, Uusimaa, Finland
Rio De Janeiro, , Brazil
Hachioji Shi, Tokyo, Japan
Madrid, Madrid, Comunidad De, Spain
Philadelphia, Pennsylvania, United States
Pune, Maharashtra, India
Fuzhou Fujian, Fujian, China
Wuhu Shi, Anhui, China
Suzhou, Jiangsu, China
Seoul, Seodaemun Gu, Korea, Republic Of
Sacramento, California, United States
Statesboro, Georgia, United States
El Paso, Texas, United States
Ciudad Autónoma De Buenos Aire, Buenos Aires, Argentina
Rosario, Santa Fe, Argentina
La Rioja, , Argentina
Vienna, Wien, Austria
Anderlecht, Bruxelles Capitale, Région De, Belgium
Charleroi, Hainaut, Belgium
La Louvière, Hainaut, Belgium
Verviers, , Belgium
Goiânia, Goiás, Brazil
Belem, Pará, Brazil
Porto Alegre, Rio Grande Do Sul, Brazil
Porto Alegre, Rio Grande, Brazil
Porto Velho, Rondônia, Brazil
Sao Paulo, São Paulo, Brazil
Sao Paulo, São Paulo, Brazil
São José Do Rio Preto, São Paulo, Brazil
Brasilia, , Brazil
Porto Alegre, , Brazil
Rio De Janeiro, , Brazil
Rio De Janeiro, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
São Paulo, , Brazil
Surrey, British Columbia, Canada
Guangzhou, Guangdong, China
Tianjing, Tianjin, China
Kunming, Yunnan, China
Hradec Kralove, , Czechia
Perpignan, Pyrénées Orientales, France
Avignon, Vaucluse, France
Créteil, île De France, France
Tübingen, Baden Württemberg, Germany
Wiesbaden, Hessen, Germany
Bottrop, Nordrhein Westfalen, Germany
Herne, Nordrhein Westfalen, Germany
Krefeld, Nordrhein Westfalen, Germany
Dessau, Sachsen Anhalt, Germany
Berlin, , Germany
Goettingen, , Germany
Patras, Achaḯa, Greece
Ioannina, Ioánnina, Greece
Hksar, , Hong Kong
New Delhi, Delhi, India
Ahmedabad, Gujarat, India
Belgaum, Karnataka, India
Pune, Maharashtra, India
Cork, , Ireland
Bologna, Emilia Romagna, Italy
Monza, Lombardia, Italy
Statte, Taranto, Italy
Cheongju Si, Chungcheongbuk Do [Chungbuk], Korea, Republic Of
Seongnam Si, Kyǒnggi Do, Korea, Republic Of
Busan, Pusan Kwangyǒkshi, Korea, Republic Of
Tuxtla Gutierrez, Chiapas, Mexico
Mexico City, Distrito Federal, Mexico
Mexico City, Distrito Federal, Mexico
Guadalajara, Jalisco, Mexico
Guadalajara, Jalisco, Mexico
Monterrey, Nuevo León, Mexico
Querétaro, , Mexico
Venlo, Limburg, Netherlands
Warszawa, Mazowieckie, Poland
Oswiecim, Małopolskie, Poland
Koszalin, Zachodniopomorskie, Poland
Lisboa, , Portugal
Cluj Napoca, Cluj, Romania
Timișoara, Timiș, Romania
Bratislava, Bratislavský Kraj, Slovakia
Almeria, Andalucía, Spain
Mahon, Balears [Baleares], Spain
Barcelona, Barcelona [Barcelona], Spain
Barcelona, Catalunya [Cataluña], Spain
Cáceres, Extremadura, Spain
Getafe, Madrid, Comunidad De, Spain
Bilbao, País Vasco, Spain
Valencia, Valenciana, Comunitat, Spain
Málaga, , Spain
Segovia, , Spain
Mugla, Muğla, Turkey
Antalya, , Turkey
Istanbul, , Turkey
Istanbul, , Turkey
Izmir, , Turkey
Samsun, , Turkey
Nishinomiya, Hyogo, Japan
Bengbu, Anhui, China
Izmir, Karsiyaka, İzmir, Turkey
Savannah, Georgia, United States
Daphne, Alabama, United States
Glendale, Arizona, United States
Tucson, Arizona, United States
Orange, California, United States
Lakewood, Colorado, United States
Palm Beach, Florida, United States
Pensacola, Florida, United States
Annapolis, Maryland, United States
Minneapolis, Minnesota, United States
Albany, New York, United States
Johnson City, New York, United States
Tigard, Oregon, United States
Austin, Texas, United States
Beaumont, Texas, United States
Fort Worth, Texas, United States
Fredericksburg, Texas, United States
Mckinney, Texas, United States
Plano, Texas, United States
Sugar Land, Texas, United States
The Woodlands, Texas, United States
Webster, Texas, United States
Norfolk, Virginia, United States
Reston, Virginia, United States
Ballarat Central, Victoria, Australia
Lodelinsart, Hainaut, Belgium
Ribeirão Preto, São Paulo, Brazil
Rio De Janeiro, , Brazil
Jining, Shandong, China
Yuncheng Shi, Shanxi, China
Ostrava, Moravskoslezský Kraj, Czechia
Helsinki, Uusimaa, Finland
Stuttgart, Baden Württemberg, Germany
Düsseldorf, Nordrhein Westfalen, Germany
Recklinghausen, Nordrhein Westfalen, Germany
Nordhausen, Thüringen, Germany
Ahmedabad, Gujarat, India
Belagavi, Karnataka, India
Jodhpur, Rajasthan, India
Chennai, Tamil Nadu, India
León, Guanajuato, Mexico
Hoofddorp, Noord Holland, Netherlands
Hengelo, Overijssel, Netherlands
Delft, Zuid Holland, Netherlands
Siedlce, Mazowieckie, Poland
Lisbon, Lisboa, Portugal
Bratislava, Bratislavský Kraj, Slovakia
Lleida, Lleida [Lérida], Spain
Valencia, València, Spain
La Tronche, Isère, France
Dordrecht, Zuid Holland, Netherlands
Waterford, , Ireland
El Paso, Texas, United States
Vienna, Wien, Austria
Köln, Nordrhein Westfalen, Germany
Prague, Praha 8, Czechia
Paris, île De France, France
Breda, Noord Brabant, Netherlands
Canton, Ohio, United States
München, Bayern, Germany
Sao Paulo, São Paulo, Brazil
Rio De Janeiro, , Brazil
Fresno, California, United States
Mountain View, California, United States
Palm Bay, Florida, United States
Westwood, Kansas, United States
Philadelphia, Pennsylvania, United States
Vienna, Wien, Austria
Auderghem, Bruxelles Capitale, Région De, Belgium
Belo Horizonte, Minas Gerais, Brazil
Recife, Pernambuco, Brazil
Sao Paulo, São Paulo, Brazil
Rio De Janeiro, , Brazil
London, Ontario, Canada
Montreal, Quebec, Canada
Rennes, Bretagne, France
Nancy, Meurthe Et Moselle, France
Friedrichshafen, Baden Württemberg, Germany
Heidelberg, Baden Württemberg, Germany
Augsburg, Bayern, Germany
Schwerin, Mecklenburg Vorpommern, Germany
Köln, Nordrhein , Germany
Trier, Rheinland Pfalz, Germany
Homburg, Saarland, Germany
Mayen, , Germany
Kanpur, Uttar Prad, India
Cork, , Ireland
Dublin, , Ireland
Dublin, , Ireland
Sligo, , Ireland
Uchinada, Ishikawa, Japan
Toluca, , Mexico
Sakarya, , Turkey
East Kilbride, Glasgow, Great Brit, United Kingdom
Germantown, Tennessee, United States
Anderlecht, , Belgium
São Paulo, , Brazil
Freehold, New Jersey, United States
Little Silver, New Jersey, United States
Augsburg, Bayern, Germany
Landshut, Bayern, Germany
Bangalore, Karnataka, India
Palma, Balears [B, Spain
Sao Paulo, São Paulo, Brazil
El Palmar, Murcia, Región De, Spain
Caba, Ciudad Autónoma De Buenos Aires, Argentina
Buenos Aires, Ciudad Aut, Argentina
Loma Linda, California, United States
Pennington, New Jersey, United States
Horsham, Pennsylvania, United States
Berazategui, Buenos Air, Argentina
Buenos Aires, Buenos Air, Argentina
Ciudad Autónoma De Buenos Aire, Buenos Air, Argentina
Buenos Aires, Ciudad Aut, Argentina
Caba, Ciudad Aut, Argentina
Caba, Ciudad Aut, Argentina
Urraween, Queensland, Australia
Ulm, Baden Württemberg, Germany
Kempten, Bayern, Germany
Statte, Taranto, Italy
Kumamoto, , Japan
Guadalajara, Jalisco, Mexico
Newton, Massachusetts, United States
San Miguel De Tucumán, Tucumán, Argentina
Phoenix, Arizona, United States
Altamonte Springs, Florida, United States
Edina, Minnesota, United States
León, Guanajuato, Mexico
Barcelona, , Spain
Heraklion, Irakleío, Greece
Zerifin, Hamerkaz, Israel
Newcastle, New South Wales, Australia
München, Bayern, Germany
Izmir, Karsiyaka, İzmir, Turkey
San Diego, California, United States
San Diego, California, United States
Eugene, Oregon, United States
Okinawa, , Japan
Ovidiu, , Romania
Ankara, , Turkey
Plantation, Florida, United States
Lake Success, New York, United States
La Rochelle, Charente Maritime, France
Naha, Okinawa, Japan
Ankara, , Turkey
Ballarat Central, Victoria, Australia
Merriam, Kansas, United States
Nea Kifissia, Attikí, Greece
Foxboro, Massachusetts, United States
Río Cuarto, Córdoba, Argentina
Donauwörth, Bayern, Germany
Nagpur, Maharashtra, India
Brussels, Bruxelles Capitale, Région De, Belgium
Belem, Pará, Brazil
Praha, Praha 5, Czechia
Shinjyuku Ku, Tokyo, Japan
Mont De Marsan, Landes, France
Porto Alegre, Rio Grande, Brazil
Hangzhou, Zhejiang, China
Jyväskylä, Mellersta Finland, Finland
Nice, Alpes Maritimes, France
Le Mans, Pays De La, France
Lyon, Rhône Alpes, France
Rome, Roma, Italy
Dallas, Texas, United States
Austin, Texas, United States
Denison, Texas, United States
Denton, Texas, United States
Flower Mound, Texas, United States
Verviers, Liège, Belgium
Limoges, Haute Vienne, France
Reims, Marne, France
Metz, Moselle, France
Bilthoven, , Netherlands
Lugo, Lugo [Lugo], Spain
Belagave, Karnataka, India
Ankara, , Turkey
Malatya, , Turkey
Brighton, Massachusetts, United States
Methuen, Massachusetts, United States
South Weymouth, Massachusetts, United States
Londonderry, New Hampshire, United States
Anderlecht, Bruxelles , Belgium
Ribeirão Preto, São Paulo, Brazil
Valenciennes, Nord, France
Lisbon, Lisboa, Portugal
Vila Nova De Gaia, Porto, Portugal
Ovidiu, Constanța, Romania
Stevenage, Hertfordsh, United Kingdom
Ciudad Madero, Tamaulipas, Mexico
Saint Cloud, Hauts De Seine, France
Adana, , Turkey
Namdong Gu, , Korea, Republic Of
Chihuahua, , Mexico
Foshan, Guangdong, China
Cincinnati, Ohio, United States
Rio De Janeiro, , Brazil
Budapest, , Hungary
Kolhapur, Maharashtra, India
Almada, Setúbal, Portugal
Wigan, Manchester, United Kingdom
Londrina, , Brazil
Hollywood, Florida, United States
Caba, Ciudad Autónoma De Buenos Aires, Argentina
Thessaloniki, , Greece
Gyeonggi Do, Yeongtong Gu, Korea, Republic Of
Seoul, , Korea, Republic Of
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Sint Niklaas, Oost Vlaanderen, Belgium
Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Dortmund, Nordrhein Westfalen, Germany
Kecskemét, Bács Kiskun, Hungary
Glendale, Arizona, United States
Baton Rouge, Louisiana, United States
Covington, Louisiana, United States
Denison, Texas, United States
Denton, Texas, United States
Flower Mound, Texas, United States
Mcallen, Texas, United States
Round Rock, Texas, United States
The Woodlands, Texas, United States
Tyler, Texas, United States
Fort Belvoir, Virginia, United States
Ciudad Autónoma De Buenos Aire, Buenos Aires, Argentina
Vienna, Wien, Austria
Salzburg, , Austria
Fortaleza, Ceará, Brazil
Sao Paulo, São Paulo, Brazil
Rio De Janeiro, , Brazil
São Paulo, , Brazil
Changchun, Jilin, China
Mont De Marsan, Landes, France
Köln, Nordrhein Westfalen, Germany
Kiel, Schleswig Holstein, Germany
Thessaloniki, Kentrikí Makedonía, Greece
Kanpur, Uttar Pradesh, India
Galway, Connaught, Ireland
Dublin, , Ireland
Ancona, , Italy
Niigata, Hokkaido, Japan
Shinjyuku Ku, Tokyo, Japan
Monterrey, Nuevo León, Mexico
Hengelo, Overijssel, Netherlands
București, , Romania
Barcelona, Catalunya [Cataluña], Spain
Sevilla, , Spain
Liverpool, , United Kingdom
Otashi, Gunma, Japan
Ankara, , Turkey
Kocaeli, , Turkey
Izmir, , Turkey
Plymouth, Devon, United Kingdom
Kecskemét, Bács Kiskun, Hungary
Viedma, Río Negro, Argentina
Athens, Attikí, Greece
Caba, , Argentina
Marrero, Louisiana, United States
Memphis, Tennessee, United States
Brussels, Bruxelles Capitale, Belgium
São Paulo, , Brazil
Köln, Nordrhein , Germany
Goettigen, , Germany
Néa Kifisiá, Attikí, Greece
Burgos, , Spain
East Kilbride, Great Brit, United Kingdom
Wigan, Manchester, United Kingdom
Karad, Maharashtra, India
Fort Collins, Colorado, United States
Visakhapatnam, Andhra Pradesh, India
Malaga, , Spain
Berkeley, California, United States
Tampa, Florida, United States
Saint Louis, Missouri, United States
Belo Horizonte, Minas Gera, Brazil
Jiangmen, Guangdong, China
Yuncheng, Shanxi, China
Clermont Ferrand, , France
Heidelberg, Baden Würt, Germany
Göttingen, , Germany
Pune, Maharashtr, India
Uchinoda, Ishikawa, Japan
Shiwa, Iwate, Japan
Namdong, , Korea, Republic Of
İzmir, , Turkey
E. Kilbride, Great Brit, United Kingdom
Lodz, , Poland
Nyiregyhaza, Szabolcs Szatmár Bereg, Hungary
Savannah, Georgia, United States
Baton Rouge, Louisiana, United States
Queens, New York, United States
Dallas, Texas, United States
Roanoke, Virginia, United States
Wien, Wienwien, Austria
São Paulo, , Brazil
Montreal, Quebec, Canada
Zhanjiang, Guangdong, China
Yongzhou, Hunan, China
Deyang, Sichuan, China
Athens, Attikí, Greece
Niigata Shi, Hokkaido, Japan
Madrid, Madrid, Comunidad De, Spain
Altindağ, Ankara, Turkey
Sakarya, , Turkey
Rochdale, Manchester, United Kingdom
Valencia, , Spain
Ciudad Autónoma De Buenos Aires, Buenos Aires, Argentina
Albuquerque, New Mexico, United States
Shenzhen, Guangdong, China
Athens, Attikí (Region), Greece
Thessaloniki, Kentrikí Makedonía, Greece
Brussels, Bruxelles Capitale, Région De, Belgium
Heidelberg, Baden Württemberg, Germany
São Paulo, , Brazil
Fuzhou, Fujian, China
Mayen, , Germany
Ahmedabad, Gujarat, India
Bucharest, București, Romania
Bucharest, București, Romania
Cluj Napoca, Cluj, Romania
Tianjing, Tianjin, China
București, , Romania
Oostende, West Vlaanderen, Belgium
București, , Romania
Quebec City, Quebec, Canada
Sao Paulo, , Brazil
El Palmar, Murcia, , Spain
Calgary, Alberta, Canada
Calgary, Alberta, Canada
Bucharest, București, Romania
Buenos Aires, , Argentina
Rio De Janeiro, , Brazil
Mayen, Rheinland Pfalz, Germany
Galway, Connaught, Ireland
Almada, Setúbal, Portugal
Singapore, Central Singapore, Singapore
Istanbul, Pendik, İstanbul, Turkey
Adapazarı, Sakarya, Turkey
Samsun, , Turkey
East Kilbride, Glasgow, Great Britain, United Kingdom
Kumamoto, , Japan
Praha, , Czechia
Auderghem, Bruxelles Capitale Région De, Belgium
Brussels, Bruxelles Capitale Région De, Belgium
Prague, , Czechia
Wiesbaden, Hessen, Germany
Athens, , Greece
Cheonan Si, , Korea, Republic Of
Getafe, , Spain
Mahon, , Spain
Sant Cugat Del Vallès, , Spain
Almeria, , Spain
Irvine, California, United States
San Miguel De Tucumán, , Argentina
Friedrichshafen, , Germany
Busan, , Korea, Republic Of
Buenos Aires, , Argentina
Gyeongsan Si, , Korea, Republic Of
Barretos, , Brazil
Monterrey, , Mexico
Ribeirão Preto, , Brazil
Sao Paulo, , Brazil
Capital, , Argentina
Vitória, , Brazil
Caba, , Argentina
São José Do Rio Preto, , Brazil
Sao Paulo, , Brazil
Athens, , Greece
Izmir, Karsiyaka, , Turkey
Monterrey, , Mexico
Río Cuarto, , Argentina
Monterrey, , Mexico
Pardubice, , Czechia
San Luis Potosi, , Mexico
Viedma, , Argentina
Fortaleza, , Brazil
Curitiba, , Brazil
Stanbul, , Turkey
Porto Velho, , Brazil
Auderghem, , Belgium
Goiânia, , Brazil
Belem, , Brazil
Sao Paulo, , Brazil
Patras, , Greece
Athens, , Greece
Nea Kifissia, , Greece
Thessaloniki, , Greece
Nyiregyhaza, , Hungary
Oswiecim, , Poland
Almada, , Portugal
Bucharest, , Romania
Bucharest, , Romania
Bucharest, , Romania
Timișoara, , Romania
Bilbao, , Spain
Istanbul, Pendik, , Turkey
Mugla, , Turkey
Tucson, Arizona, United States
Patients applied
Trial Officials
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Study Director
Eli Lilly and Company
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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