Functional Imaging of Baby Brains

Launched by HAMILTON HEALTH SCIENCES CORPORATION · Aug 23, 2022

Keywords

ClinConnect Summary

This clinical trial, titled "Functional Imaging of Baby Brains," is studying how to better predict the long-term effects of brain injuries in newborns caused by a lack of oxygen, a condition known as hypoxic-ischemic encephalopathy (HIE). Researchers want to see if a new imaging technique called diffuse optical tomography can provide helpful information alongside traditional MRI scans. The goal is to understand how severe the developmental challenges might be for these infants as they grow.

To participate in this study, babies must be admitted to the Neonatal Intensive Care Unit at McMaster Children's Hospital with a diagnosis of HIE. They should be at least 35 weeks old and weigh more than 1.8 kilograms at birth. Unfortunately, babies with certain other medical conditions or who need special breathing support will not be eligible. If your baby qualifies for the study, they will undergo non-invasive brain imaging to help researchers learn more about this serious condition. This research is important as it could lead to better care and support for infants affected by brain injuries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Newborns admitted to the McMaster Children's Hospital Neonatal Intensive Care Unit with the diagnosis of hypoxic-ischemic encephalopathy will be considered for this study
• • Gestational age of 35 weeks or greater
• • Birth weight more than 1.8 Kg
• Exclusion Criteria:
• • (i) suspected or confirmed congenital malformations, (ii) chromosomal anomalies, (iii) inborn errors of metabolism, (iv) congenital infections, (v) neonatal encephalopathy other than HIE, (vi) baby requires respiratory support in the form of CPAP, Mechanical ventilation, high flow nasal cannula and (vii) scalp injury or non-intact skin surface in the scalp