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Search / Trial NCT05518513

Continuous Infusion and Intermittent Bolus Adductor Canal Block for Total Knee Arthroplasty

Launched by NATIONAL CHENG-KUNG UNIVERSITY HOSPITAL · Aug 24, 2022

Trial Information

Current as of August 22, 2025

Recruiting

Keywords

Total Knee Arthroplasty Adductor Canal Block Nerve Block Regional Analgesia

ClinConnect Summary

This clinical trial is studying a method to help manage pain for patients undergoing total knee replacement surgery. Specifically, researchers want to see if using a continuous infusion of local anesthetics combined with shorter doses, called boluses, can better control pain compared to longer doses. The goal is to reduce pain levels and the amount of opioid medication needed after surgery.

To participate in this trial, you should be an adult planning to have a knee replacement surgery while under spinal anesthesia. You would also need to be healthy enough to cooperate during the study and not have certain conditions like allergies to the study medications, chronic pain, or neuromuscular diseases. If you choose to participate, you can expect to receive either the continuous infusion and bolus treatment or a different approach, and your pain levels and medication use will be closely monitored during your recovery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults receiving unilateral total knee arthroplasty under spinal anesthesia
  • American society of anesthesiologists 1-3
  • Exclusion Criteria:
  • Could not cooperate
  • Allergy to medicines used in the study
  • Chronic pain
  • Long term opioid use
  • Neuromuscular disease
  • Surgical complication: massive bleeding, postoperative ICU, unanticipated procedure

About National Cheng Kung University Hospital

National Cheng Kung University Hospital is a leading academic medical institution in Taiwan, dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its extensive resources and expertise in various medical fields to facilitate groundbreaking studies that enhance patient care and medical knowledge. Committed to adhering to the highest ethical standards and regulatory guidelines, National Cheng Kung University Hospital fosters collaborations with researchers, healthcare professionals, and industry partners to drive the development of new therapies and improve health outcomes for diverse populations.

Locations

Tainan, , Taiwan

Tainan, , Taiwan

Patients applied

0 patients applied

Trial Officials

WEI-TENG WENG, MD

Principal Investigator

Department of Anesthesiology, National Cheng Kung University Hospital, Taiwan

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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