Cushing's Syndrome Before and After Treatment (CORRECT)

Launched by UNIVERSITY OF AARHUS · Aug 26, 2022

Keywords

ClinConnect Summary

The clinical trial titled "Cushing's Syndrome Before and After Treatment" (CORRECT) is studying how Cushing's syndrome affects people’s daily lives and health before and after they receive treatment. Cushing's syndrome is a condition where the body produces too much of a hormone called cortisol, which can lead to various health issues. The researchers want to understand how this syndrome impacts physical health, overall quality of life, and the body's natural daily rhythms, known as circadian rhythms. They believe that treating the syndrome can help improve these aspects for patients.

To participate in this trial, individuals must be over 18 years old and have been diagnosed with Cushing's syndrome within the last two months. However, people with active cancer, certain severe heart or kidney problems, or specific liver diseases cannot join. Participants will be asked to share their experiences and health information, and they will be monitored before and after their treatment. This study aims to provide valuable insights into the effects of Cushing's syndrome and the benefits of treatment, ultimately helping to improve the lives of those affected.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * New (≤ 2 months) diagnosis of Cushing's syndrome (CS) of endogenous etiology:
• • ACTH-dependent CS
• • ACTH-independent CS
• • Age \>18 years
• • Written informed consent
• Exclusion Criteria:
• • Active cancer
• • Iatrogenic or malignant cause of CS such as adrenocortical carcinoma
• • Chronic heart failure (New York Heart Association class IV)
• • Chronic kidney disease Chronic Kidney Disease stage ≥3 (eGFR \>30 ml/min)
• • Liver disease in the form of cirrhosis
• • Deemed unable to complete the study safely by investigator