The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial
Launched by UNIVERSITY OF PITTSBURGH · Aug 29, 2022
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Nearly one million patients require invasive mechanical ventilation for acute respiratory failure in the United States each year. Most of these patients will recover to the point of extubation, yet even those who are extubated remain vulnerable to complications and poor outcomes. Multiple high-profile randomized controlled trials have shown that two preventive post-extubation respiratory therapies-noninvasive ventilation (NIV) and high-flow nasal cannula oxygen (HFNC)-can prevent recurrent respiratory failure, reintubation, and death in this population. Despite this evidence, however, these...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All adults treated with invasive mechanical ventilation \>24 hours in participating ICUs
- Exclusion Criteria:
- • None
About University Of Pittsburgh
The University of Pittsburgh is a leading research institution known for its commitment to advancing medical science and improving patient care through innovative clinical trials. With a robust infrastructure for research and a multidisciplinary approach, the university fosters collaboration among experts in various fields, facilitating the development of novel therapies and interventions. Its clinical trial programs emphasize ethical standards, patient safety, and the integration of cutting-edge technology, making the University of Pittsburgh a pivotal contributor to the landscape of clinical research and a trusted partner in the pursuit of health advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
New Castle, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Monroeville, Pennsylvania, United States
York, Pennsylvania, United States
Harrisburg, Pennsylvania, United States
Carlisle, Pennsylvania, United States
Hanover, Pennsylvania, United States
Harrisburg, Pennsylvania, United States
Mechanicsburg, Pennsylvania, United States
Patients applied
Trial Officials
Timothy D Girard, MD, MSCI
Principal Investigator
University of Pittsburgh
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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