Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris

Launched by ASSIUT UNIVERSITY · Sep 7, 2022

Keywords

ClinConnect Summary

Several treatment modalities have been used to treat AV. Topical therapies include antibiotics, azelaic acid, benzoyl peroxide, and retinoids. Systemic treatments include antibiotics, hormonal therapy, and isotretinoin in addition to physical modalities as chemical peeling .

Chemical peeling is a safe, efficacious, and cost-effective procedure for treating various skin disorders and for enhancing cosmetic appearance. The principle of peeling involves controlled chemical injury to the skin in order to promote it to rejuvenate, leading to smoothening of the skin and improvement of its surfac...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Both males and females will be included.
• • Patients older than 18 years of age.
• • Patients with mild and moderate AV.
• • Patients with Fitzpatrick skin type III, IV and V.
• Exclusion Criteria:
• • Severe acne.
• • Patients under treatment with contraceptive pills or received any kinds of systemic or topical acne medication in the last 2 months (isotretinoin, antibiotics, topical products) or corticosteroid, lithium, growth hormone, systemic metformin, vitamin B12, whey proteins, and estrogenic-progestogens.
• • History of hypertrophic/keloid scar formation.
• • Pregnancy and lactation.
• • Recurrent herpes infection.
• • Subjects with diseases that affect IGF-1 levels such as diabetes, metabolic syndrome, and acromegaly.
• • Conditions that affect liver or thyroid function, celiac disease and inflammatory bowel diseases.